AutismKB 2.0

Annotation Details for ASH1L


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Basic Information Top
Gene Symbol:ASH1L ( ASH1,ASH1L1,FLJ10504,KIAA1420,KMT2H )
Gene Full Name: ash1 (absent, small, or homeotic)-like (Drosophila)
Band: 1q22
Quick LinksEntrez ID:55870; OMIM: 607999; Uniprot ID:ASH1L_HUMAN; ENSEMBL ID: ENSG00000116539; HGNC ID: 19088
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634TAS-nucleus10860993
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005694IEA-chromosome-
GO:0005794IDA-Golgi apparatus-
GO:0005923IEA-bicellular tight junction-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003682IEA-chromatin binding-
GO:0018024TAS-histone-lysine N-methyltransferase activity-
GO:0042800IEA-histone methyltransferase activity (H3-K4 specific)-
GO:0046872IEA-metal ion binding-
GO:0046975IDA-histone methyltransferase activity (H3-K36 specific)26002201
GO ID Evidence Qualifier GO_term References
GO:0001501IEA-skeletal system development-
GO:0002674IEA-negative regulation of acute inflammatory response-
GO:0006323TAS-DNA packaging10860993
GO:0006366TAS-transcription from RNA polymerase II promoter10860993
GO:0007267TAS-cell-cell signaling10860993
GO:0007338IEA-single fertilization-
GO:0009791IEA-post-embryonic development-
GO:0032635IEA-interleukin-6 production-
GO:0043124IEA-negative regulation of I-kappaB kinase/NF-kappaB signaling-
GO:0043409IEA-negative regulation of MAPK cascade-
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0046697IEA-decidualization-
GO:0051568IEA-histone H3-K4 methylation-
GO:0061038IEA-uterus morphogenesis-
GO:0097676IDA-histone H3-K36 dimethylation26002201
GO:0097722IEA-sperm motility-
GO:1903699IEA-tarsal gland development-
GO:1903709IEA-uterine gland development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ASH1LH3F3A10927217403666 Affinity Capture-MS
ASH1LH3F3A12096917403666 Affinity Capture-MS
ASH1LHIST1H3A11394617923682 Biochemical Activity
ASH1LHIST1H3A12096917923682 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2183158
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6101'