AutismKB 2.0

Annotation Details for PBK


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Basic Information Top
Gene Symbol:PBK ( CT84,FLJ14385,Nori-3,SPK,TOPK )
Gene Full Name: PDZ binding kinase
Band: 8p21.1
Quick LinksEntrez ID:55872; OMIM: 611210; Uniprot ID:TOPK_HUMAN; ENSEMBL ID: ENSG00000168078; HGNC ID: 18282
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005575ND-cellular_component-
GO:0005634IDA-nucleus25575812
GO ID Evidence Qualifier GO_term References
GO:0004674TAS-protein serine/threonine kinase activity10779557
GO:0005515IPI-protein binding10779557
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0000278NAS-mitotic cell cycle10779557
GO:0006468IEA-protein phosphorylation-
GO:0032435IEA-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-
GO:0032873IEA-negative regulation of stress-activated MAPK cascade-
GO:0034644IEA-cellular response to UV-
GO:0050728IEA-negative regulation of inflammatory response-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PBKARAF12097112620389 Two-hybrid
PBKARAF10686412620389 Two-hybrid
PBKGPS210913216169070 Two-hybrid
PBKGPS212097116169070 Two-hybrid
PBKH2AFX12097117145805 Biochemical Activity; Reconstituted Complex
PBKH2AFX10926817145805 Biochemical Activity; Reconstituted Complex
PBKTRIM3711067816189514 Two-hybrid
PBKTRIM3712097116189514 Two-hybrid
PBKGPRASP111508616169070 Two-hybrid
PBKGPRASP112097116169070 Two-hybrid
KIAA1377PBK12161716169070 Two-hybrid
KIAA1377PBK12097116169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1289156
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030523-2'