AutismKB 2.0

Annotation Details for PRKG1


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Basic Information Top
Gene Symbol:PRKG1 ( CGKI,DKFZp686K042,FLJ36117,MGC71944,PGK,PKG,PRKG1B,PRKGR1B,cGKI-BETA,cGKI-alpha )
Gene Full Name: protein kinase, cGMP-dependent, type I
Band: 10q11.23-q21.1
Quick LinksEntrez ID:5592; OMIM: 176894; Uniprot ID:KGP1_HUMAN; ENSEMBL ID: ENSG00000185532; HGNC ID: 9414
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm21402151
GO:0005794IEA-Golgi apparatus-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane21402151
GO ID Evidence Qualifier GO_term References
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0004692IDA-cGMP-dependent protein kinase activity21402151
GO:0004692TAS-cGMP-dependent protein kinase activity-
GO:0005246IDA-calcium channel regulator activity21402151
GO:0005515IPI-protein binding16990611
GO:0005524IEA-ATP binding-
GO:0030553IEA-cGMP binding-
GO ID Evidence Qualifier GO_term References
GO:0001764IEA-neuron migration-
GO:0006468IDANOTprotein phosphorylation15905169
GO:0007165TAS-signal transduction2792381
GO:0016358IEA-dendrite development-
GO:0019934IEA-cGMP-mediated signaling-
GO:0030036TAS-actin cytoskeleton organization10851246
GO:0030900IEA-forebrain development-
GO:0043087IMP-regulation of GTPase activity14608379
GO:0060087IEA-relaxation of vascular smooth muscle-
GO:0090331IMP-negative regulation of platelet aggregation16990611
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PRKG1GAPDH1115789308888 Affinity Capture-Western
PRKG1GAPDH1088689308888 Affinity Capture-Western
PRKG1GTF2I11157812082086 Affinity Capture-Western; Reconstituted Complex
PRKG1GTF2I10922412082086 Affinity Capture-Western; Reconstituted Complex
PRKG1ITPR111157810724174 Affinity Capture-Western; Biochemical Activity
PRKG1ITPR110991310724174 Affinity Capture-Western; Biochemical Activity
PRKG1PPP1R12A11157810567269 Reconstituted Complex
PRKG1PPP1R12A11074210567269 Reconstituted Complex
PRKG1PPP1R12B11157810567269 Two-hybrid
PRKG1PPP1R12B11074310567269 Two-hybrid
PRKG1NPR111094112855709 Two-hybrid
PRKG1NPR111157812855709 Two-hybrid
TNNT1PRKG111157810601315 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
TNNT1PRKG111299210601315 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
MRVI1PRKG111561710724174 11309393 Affinity Capture-Western; Biochemical Activity; Two-hybrid
MRVI1PRKG111157810724174 11309393 Affinity Capture-Western; Biochemical Activity; Two-hybrid
RAF1PRKG111183112237340 Affinity Capture-Western
RAF1PRKG111157812237340 Affinity Capture-Western
RGS2PRKG111192914608379 Affinity Capture-Western; Reconstituted Complex
RGS2PRKG111157814608379 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:108174
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1308'