AutismKB 2.0

Annotation Details for MAPK10


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Basic Information Top
Gene Symbol:MAPK10 ( FLJ12099,FLJ33785,JNK3,JNK3A,MGC50974,PRKM10,p493F12,p54bSAPK )
Gene Full Name: mitogen-activated protein kinase 10
Band: 4q21.3
Quick LinksEntrez ID:5602; OMIM: 602897; Uniprot ID:MK10_HUMAN; ENSEMBL ID: ENSG00000109339; HGNC ID: 6872
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IBA-nucleus-
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005737ISS-cytoplasm-
GO:0005739ISS-mitochondrion-
GO:0005829TAS-cytosol-
GO:0005886ISS-plasma membrane-
GO:0043005IBA-neuron projection-
GO ID Evidence Qualifier GO_term References
GO:0004705IBA-JUN kinase activity-
GO:0004705ISS-JUN kinase activity8654373
GO:0004708TAS-MAP kinase kinase activity7826642
GO:0005515IPI-protein binding19294699
GO:0005524IEA-ATP binding-
GO ID Evidence Qualifier GO_term References
GO:0000187IEA-activation of MAPK activity-
GO:0006468IMP-protein phosphorylation22441692
GO:0006468ISS-protein phosphorylation-
GO:0007165TAS-signal transduction8654373
GO:0007254IBA-JNK cascade-
GO:0007254ISS-JNK cascade8654373
GO:0007254TAS-JNK cascade-
GO:0007258IEA-JUN phosphorylation-
GO:0009416ISS-response to light stimulus-
GO:0010468IBA-regulation of gene expression-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0042752ISS-regulation of circadian rhythm-
GO:0048511IEA-rhythmic process-
GO:0048666IBA-neuron development-
GO:0051090TAS-regulation of sequence-specific DNA binding transcription factor activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAPK10ARRB110690111356842 Affinity Capture-Western
MAPK10ARRB111158811356842 Affinity Capture-Western
MAPK10ARRB210690211356842 Affinity Capture-Western
MAPK10ARRB211158811356842 Affinity Capture-Western
MAPK10CREBBP10777720936779 Two-hybrid
MAPK10CREBBP11158820936779 Two-hybrid
MAPK10DUSP110817611359773 Affinity Capture-Western
MAPK10DUSP111158811359773 Affinity Capture-Western
MAPK10GTF3C110923016169070 Two-hybrid
MAPK10GTF3C111158816169070 Two-hybrid
MAPK10HDAC110931516611996 Affinity Capture-Western
MAPK10HDAC111158816611996 Affinity Capture-Western
MAPK10MCL111033817670986 Biochemical Activity
MAPK10MCL111158817670986 Biochemical Activity
TP53MAPK101130109393873 Affinity Capture-Western
TP53MAPK101115889393873 Affinity Capture-Western
MAPK8IP3MAPK1011677410523642 10629060 12189133 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
MAPK8IP3MAPK1011158810523642 10629060 12189133 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
MAPK8IP2MAPK1011708610756100 Reconstituted Complex
MAPK8IP2MAPK1011158810756100 Reconstituted Complex
DUSP10MAPK1011638911359773 Affinity Capture-Western
DUSP10MAPK1011158811359773 Affinity Capture-Western
DUSP16MAPK1012332111359773 Affinity Capture-Western
DUSP16MAPK1011158811359773 Affinity Capture-Western
SH3BP5MAPK1011485312167088 Reconstituted Complex
SH3BP5MAPK1011158812167088 Reconstituted Complex
UNC119MAPK1011454816169070 Two-hybrid
UNC119MAPK1011158816169070 Two-hybrid
HDAC9MAPK1011508316611996 Affinity Capture-Western; Reconstituted Complex
HDAC9MAPK1011158816611996 Affinity Capture-Western; Reconstituted Complex
KIF26AMAPK1011758420936779 Two-hybrid
KIF26AMAPK1011158820936779 Two-hybrid
CEP290MAPK1012316320936779 Two-hybrid
CEP290MAPK1011158820936779 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1346863
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-051120-117'