Annotation Details for MAPK13

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Basic Information Top

Gene Symbol:	MAPK13 ( MGC99536,PRKM13,SAPK4,p38delta )
Gene Full Name:	mitogen-activated protein kinase 13
Band:	6p21.31
Quick Links	Entrez ID:5603; OMIM: 602899; Uniprot ID:MK13_HUMAN; ENSEMBL ID: ENSG00000156711; HGNC ID: 6875
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:4 results
Biological Process:12 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005634	IBA	-	nucleus	-
GO:0005737	IBA	-	cytoplasm	-
GO:0005829	TAS	-	cytosol	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004674	IDA	-	protein serine/threonine kinase activity	12244047
GO:0004707	IDA	-	MAP kinase activity	9218798
GO:0005515	IPI	-	protein binding	19135240
GO:0005524	IEA	-	ATP binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000165	IEA	-	MAPK cascade	-
GO:0006351	IEA	-	transcription, DNA-templated	-
GO:0006355	IEA	-	regulation of transcription, DNA-templated	-
GO:0006950	IDA	-	response to stress	9218798
GO:0006970	IDA	-	response to osmotic stress	9731215
GO:0007049	IEA	-	cell cycle	-
GO:0010468	IBA	-	regulation of gene expression	-
GO:0018105	IDA	-	peptidyl-serine phosphorylation	15850461
GO:0032755	IMP	-	positive regulation of interleukin-6 production	19279008
GO:0035556	IDA	-	intracellular signal transduction	9218798
GO:0048010	TAS	-	vascular endothelial growth factor receptor signaling pathway	-
GO:0050729	IC	-	positive regulation of inflammatory response	19279008

Protein-Protein Interaction

BioGRID:6 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
MAPK13	ATF2	107776	12244047	Biochemical Activity
MAPK13	ATF2	111589	12244047	Biochemical Activity
MAPK13	FGF12	108548	12244047	Biochemical Activity
MAPK13	FGF12	111589	12244047	Biochemical Activity
MAPK8IP2	MAPK13	117086	11378392 12244047	Affinity Capture-Western
MAPK8IP2	MAPK13	111589	11378392 12244047	Affinity Capture-Western

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1346864
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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