Annotation Details for MAP2K6
Basic Information Top
Gene Symbol: | MAP2K6 ( MAPKK6,MEK6,MKK6,PRKMK6,SAPKK3 ) |
---|---|
Gene Full Name: | mitogen-activated protein kinase kinase 6 |
Band: | 17q24.3 |
Quick Links | Entrez ID:5608; OMIM: 601254; Uniprot ID:MP2K6_HUMAN; ENSEMBL ID: ENSG00000108984; HGNC ID: 6846 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IDA | - | nucleus | - |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005737 | IBA | - | cytoplasm | - |
GO:0005829 | IDA | - | cytosol | - |
GO:0005829 | TAS | - | cytosol | - |
GO:0005856 | IEA | - | cytoskeleton | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0004674 | TAS | - | protein serine/threonine kinase activity | - |
GO:0004702 | IBA | - | signal transducer, downstream of receptor, with serine/threonine kinase activity | - |
GO:0004708 | IBA | - | MAP kinase kinase activity | - |
GO:0004708 | TAS | - | MAP kinase kinase activity | - |
GO:0004713 | IEA | - | protein tyrosine kinase activity | - |
GO:0005515 | IPI | - | protein binding | 11035004 |
GO:0005524 | IEA | - | ATP binding | - |
GO:0019901 | IPI | - | protein kinase binding | 11279118 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000165 | IEA | - | MAPK cascade | - |
GO:0000187 | TAS | - | activation of MAPK activity | - |
GO:0002931 | IEA | - | response to ischemia | - |
GO:0006351 | IEA | - | transcription, DNA-templated | - |
GO:0006355 | IEA | - | regulation of transcription, DNA-templated | - |
GO:0006915 | IEA | - | apoptotic process | - |
GO:0006975 | TAS | - | DNA damage induced protein phosphorylation | 10848581 |
GO:0007050 | TAS | - | cell cycle arrest | 10848581 |
GO:0007165 | TAS | - | signal transduction | 8621675 |
GO:0018108 | IEA | - | peptidyl-tyrosine phosphorylation | - |
GO:0022602 | IEA | - | ovulation cycle process | - |
GO:0032308 | IEA | - | positive regulation of prostaglandin secretion | - |
GO:0035897 | TAS | - | proteolysis in other organism | - |
GO:0042493 | IEA | - | response to drug | - |
GO:0043065 | IEA | - | positive regulation of apoptotic process | - |
GO:0051770 | IEA | - | positive regulation of nitric-oxide synthase biosynthetic process | - |
GO:0060048 | IEA | - | cardiac muscle contraction | - |
GO:0070423 | TAS | - | nucleotide-binding oligomerization domain containing signaling pathway | - |
GO:0072709 | IEA | - | cellular response to sorbitol | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
MAP2K6 | MAPK14 | 111594 | 8622669 8626699 11279118 12697810 | Biochemical Activity |
MAP2K6 | MAPK14 | 107819 | 8622669 8626699 11279118 12697810 | Biochemical Activity |
MAP2K6 | SMAD7 | 110267 | 12589052 | Affinity Capture-Western |
MAP2K6 | SMAD7 | 111594 | 12589052 | Affinity Capture-Western |
MAP2K6 | MAP3K4 | 110380 | 9841871 | Biochemical Activity |
MAP2K6 | MAP3K4 | 111594 | 9841871 | Biochemical Activity |
MAP2K6 | MAP3K5 | 111594 | 11689443 12820963 | Biochemical Activity; Reconstituted Complex |
MAP2K6 | MAP3K5 | 110381 | 11689443 12820963 | Biochemical Activity; Reconstituted Complex |
MAP2K6 | NPHS1 | 110928 | 11562357 | Phenotypic Suppression |
MAP2K6 | NPHS1 | 111594 | 11562357 | Phenotypic Suppression |
MAP2K6 | PLCB2 | 111346 | 12054652 | Affinity Capture-Western |
MAP2K6 | PLCB2 | 111594 | 12054652 | Affinity Capture-Western |
MAP2K6 | MAP2K3 | 111594 | 11562357 | Phenotypic Enhancement |
MAP2K6 | MAP2K3 | 111592 | 11562357 | Phenotypic Enhancement |
MAP3K7 | MAP2K6 | 112748 | 10094049 10838074 11460167 14633987 | Biochemical Activity |
MAP3K7 | MAP2K6 | 111594 | 10094049 10838074 11460167 14633987 | Biochemical Activity |
TAOK2 | MAP2K6 | 114750 | 11279118 | Affinity Capture-Western; Biochemical Activity |
TAOK2 | MAP2K6 | 111594 | 11279118 | Affinity Capture-Western; Biochemical Activity |
No data |
No data |
- MGI ID: MGI:1346870
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-010202-3