Annotation Details for PRLR


Gene Symbol: | PRLR ( hPRLrI ) |
---|---|
Gene Full Name: | prolactin receptor |
Band: | 5p13.2 |
Quick Links | Entrez ID:5618; OMIM: 176761; Uniprot ID:PRLR_HUMAN; ENSEMBL ID: ENSG00000113494; HGNC ID: 9446 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005576 | IEA | - | extracellular region | - |
GO:0005886 | TAS | - | plasma membrane | - |
GO:0009986 | IDA | - | cell surface | 10585417 |
GO:0016021 | IEA | - | integral component of membrane | - |
GO:0031904 | TAS | - | endosome lumen | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0004925 | NAS | - | prolactin receptor activity | 10585417 |
GO:0005515 | IPI | - | protein binding | 12819209 |
GO:0017046 | IPI | - | peptide hormone binding | 7984244 |
GO:0042803 | NAS | - | protein homodimerization activity | 10585417 |
GO:0042978 | NAS | - | ornithine decarboxylase activator activity | 10585417 |
GO:0046872 | IEA | - | metal ion binding | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0006694 | NAS | - | steroid biosynthetic process | 10585417 |
GO:0007166 | NAS | - | cell surface receptor signaling pathway | 10585417 |
GO:0007171 | IDA | - | activation of transmembrane receptor protein tyrosine kinase activity | 10585417 |
GO:0007566 | TAS | - | embryo implantation | 9009200 |
GO:0007595 | NAS | - | lactation | 10585417 |
GO:0030155 | IEA | - | regulation of cell adhesion | - |
GO:0030856 | IEA | - | regulation of epithelial cell differentiation | - |
GO:0038161 | IEA | - | prolactin signaling pathway | - |
GO:0042110 | NAS | - | T cell activation | 10585417 |
GO:0042976 | NAS | - | activation of Janus kinase activity | 10585417 |
GO:0043066 | NAS | - | negative regulation of apoptotic process | 10585417 |
GO:0060397 | TAS | - | JAK-STAT cascade involved in growth hormone signaling pathway | - |
GO:0060644 | IEA | - | mammary gland epithelial cell differentiation | - |
GO:0060736 | IEA | - | prostate gland growth | - |
GO:0060749 | IEA | - | mammary gland alveolus development | - |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
PRLR | GTF3A | 111603 | 18573876 | Affinity Capture-Western |
PRLR | GTF3A | 109226 | 18573876 | Affinity Capture-Western |
PRLR | JAK2 | 111603 | 9202403 | Affinity Capture-Western |
PRLR | JAK2 | 109920 | 9202403 | Affinity Capture-Western |
PRLR | PPIA | 111603 | 12668872 | Affinity Capture-Western; Reconstituted Complex |
PRLR | PPIA | 111474 | 12668872 | Affinity Capture-Western; Reconstituted Complex |
VAV1 | PRLR | 113252 | 7768923 11328862 | Affinity Capture-Western; Reconstituted Complex |
VAV1 | PRLR | 111603 | 7768923 11328862 | Affinity Capture-Western; Reconstituted Complex |
SOCS2 | PRLR | 114362 | 10455112 | Affinity Capture-Western |
SOCS2 | PRLR | 111603 | 10455112 | Affinity Capture-Western |
PTPN11 | PRLR | 111603 | 10991949 | Affinity Capture-Western |
PTPN11 | PRLR | 111745 | 10991949 | Affinity Capture-Western |
TEC | PRLR | 111603 | 11328862 | Affinity Capture-Western; Reconstituted Complex |
TEC | PRLR | 112865 | 11328862 | Affinity Capture-Western; Reconstituted Complex |
SOCS3 | PRLR | 111603 | 11713228 | Affinity Capture-Western |
SOCS3 | PRLR | 114488 | 11713228 | Affinity Capture-Western |
UBC | PRLR | 111603 | 15082796 18573876 | Affinity Capture-Western |
UBC | PRLR | 113164 | 15082796 18573876 | Affinity Capture-Western |
FBXW11 | PRLR | 111603 | 15082796 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
FBXW11 | PRLR | 116887 | 15082796 | Affinity Capture-Western; Biochemical Activity; Reconstituted Complex |
No data |
No data |
- MGI ID: MGI:97763
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-070705-155