AutismKB 2.0

Annotation Details for PARD3


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Basic Information Top
Gene Symbol:PARD3 ( ASIP,Baz,Bazooka,FLJ21015,PAR3,PAR3alpha,PARD3A,SE2-5L16,SE2-5LT1,SE2-5T2 )
Gene Full Name: par-3 partitioning defective 3 homolog (C. elegans)
Band: 10p11.22-p11.21
Quick LinksEntrez ID:56288; OMIM: 606745; Uniprot ID:PARD3_HUMAN; ENSEMBL ID: ENSG00000148498; HGNC ID: 16051
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0005886TAS-plasma membrane-
GO:0005911IDA-cell-cell junction20332120
GO:0005911ISS-cell-cell junction-
GO:0005923IDA-bicellular tight junction14676191
GO:0005923ISS-bicellular tight junction-
GO:0005938IEA-cell cortex-
GO:0012505IEA-endomembrane system-
GO:0030054IDA-cell junction-
GO:0030054TAS-cell junction-
GO:0033269ISS-internode region of axon-
GO:0043025IEA-neuronal cell body-
GO:0043234IEA-protein complex-
GO:0044295IEA-axonal growth cone-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding10934474
GO:0005546ISS-phosphatidylinositol-4,5-bisphosphate binding-
GO:0005547ISS-phosphatidylinositol-3,4,5-trisphosphate binding-
GO:0019903IEA-protein phosphatase binding-
GO:0032266ISS-phosphatidylinositol-3-phosphate binding-
GO ID Evidence Qualifier GO_term References
GO:0006461TAS-protein complex assembly10934474
GO:0006612ISS-protein targeting to membrane-
GO:0007049IEA-cell cycle-
GO:0007163TAS-establishment or maintenance of cell polarity14676191
GO:0007179TAS-transforming growth factor beta receptor signaling pathway-
GO:0007205TAS-protein kinase C-activating G-protein coupled receptor signaling pathway11260256
GO:0007409TAS-axonogenesis14676191
GO:0008356TAS-asymmetric cell division10934474
GO:0010801ISS-negative regulation of peptidyl-threonine phosphorylation-
GO:0022011ISS-myelination in peripheral nervous system-
GO:0031643ISS-positive regulation of myelination-
GO:0060341IEA-regulation of cellular localization-
GO:0070830ISS-bicellular tight junction assembly-
GO:0070830TAS-bicellular tight junction assembly-
GO:0090162ISS-establishment of epithelial cell polarity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PARD3ECT210822315254234 Affinity Capture-Western
PARD3ECT212113415254234 Affinity Capture-Western
PARD3SFN10907215778465 Affinity Capture-MS
PARD3SFN12113415778465 Affinity Capture-MS
PARD3PRKCI12113412459187 Affinity Capture-Western; Reconstituted Complex
PARD3PRKCI11157012459187 Affinity Capture-Western; Reconstituted Complex
PARD3PRKCZ12113412459187 Affinity Capture-Western
PARD3PRKCZ11157612459187 Affinity Capture-Western
PARD3YWHAB11336117353931 Affinity Capture-MS
PARD3YWHAB12113417353931 Affinity Capture-MS
PARD3YWHAG12113417353931 Affinity Capture-MS
PARD3YWHAG11336417353931 Affinity Capture-MS
PARD3PVRL312113412515806 Affinity Capture-Western; Reconstituted Complex
PARD3PVRL311744112515806 Affinity Capture-Western; Reconstituted Complex
PARD3F11R11915312953056 Reconstituted Complex
PARD3F11R12113412953056 Reconstituted Complex
PARD3PARD6A12113412459187 Affinity Capture-Western
PARD3PARD6A11915712459187 Affinity Capture-Western
PARD6GPARD312113412459187 Affinity Capture-Western
PARD6GPARD312413512459187 Affinity Capture-Western
PARD6BPARD312113412459187 Affinity Capture-Western
PARD6BPARD312414512459187 Affinity Capture-Western
JAM2PARD312113412953056 Affinity Capture-Western; Reconstituted Complex
JAM2PARD312182412953056 Affinity Capture-Western; Reconstituted Complex
JAM3PARD312113412953056 Affinity Capture-Western; Reconstituted Complex
JAM3PARD312373412953056 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2135608
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030925-47'