AutismKB 2.0

Annotation Details for LGMN


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Basic Information Top
Gene Symbol:LGMN ( AEP,LGMN1,PRSC1 )
Gene Full Name: legumain
Band: 14q32.12
Quick LinksEntrez ID:5641; OMIM: 602620; Uniprot ID:LGMN_HUMAN; ENSEMBL ID: ENSG00000100600; HGNC ID: 9472
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005764ISS-lysosome-
GO:0005770IEA-late endosome-
GO:0036021TAS-endolysosome lumen-
GO:0043202TAS-lysosomal lumen-
GO:0045177IEA-apical part of cell-
GO:0070062IDA-extracellular exosome23533145
GO ID Evidence Qualifier GO_term References
GO:0004197IBA-cysteine-type endopeptidase activity-
GO:0004197ISS-cysteine-type endopeptidase activity9065484
GO:0004197TAS-cysteine-type endopeptidase activity-
GO:0008233IDA-peptidase activity136644
GO ID Evidence Qualifier GO_term References
GO:0002224TAS-toll-like receptor signaling pathway-
GO:0003014ISS-renal system process-
GO:0006508ISS-proteolysis9065484
GO:0006624IBA-vacuolar protein processing-
GO:0010447IEA-response to acidic pH-
GO:0019886TAS-antigen processing and presentation of exogenous peptide antigen via MHC class II-
GO:0032801ISS-receptor catabolic process-
GO:0040015IEA-negative regulation of multicellular organism growth-
GO:0042359TAS-vitamin D metabolic process-
GO:0043524IGI-negative regulation of neuron apoptotic process18374643
GO:0051603IBA-proteolysis involved in cellular protein catabolic process-
GO:0051603ISS-proteolysis involved in cellular protein catabolic process-
GO:1901185ISS-negative regulation of ERBB signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
USP17LGMN11162419615732 Affinity Capture-MS
USP17LGMN13399019615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1330838
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-021030-1'