AutismKB 2.0

Annotation Details for PRSS3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PRSS3 ( MTG,PRSS4,T9,TRY3,TRY4 )
Gene Full Name: protease, serine, 3
Band: 9p13.3
Quick LinksEntrez ID:5646; OMIM: 613578; Uniprot ID:TRY3_HUMAN; ENSEMBL ID: ENSG00000010438; HGNC ID: 9486
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space6698368
GO:0070062IDA-extracellular exosome23376485
GO:1904724TAS-tertiary granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0004252IDA-serine-type endopeptidase activity6698368
GO:0005509IDA-calcium ion binding6698368
GO:0005515IPI-protein binding6698368
GO:0008236TAS-serine-type peptidase activity-
GO ID Evidence Qualifier GO_term References
GO:0006508IDA-proteolysis6698368
GO:0006508NAS-proteolysis8294000
GO:0007586TAS-digestion6698368
GO:0009235TAS-cobalamin metabolic process-
GO:0019730TAS-antimicrobial humoral response-
GO:0031638IDA-zymogen activation6698368
GO:0043312TAS-neutrophil degranulation-
GO:0043542IMP-endothelial cell migration15313892
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TFPIPRSS31116287498454 Co-crystal Structure
TFPIPRSS31128937498454 Co-crystal Structure
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1914623
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved