Gene Symbol:	RELN ( PRO1598,RL )
Gene Full Name:	reelin
Band:	7q22.1
Quick Links	Entrez ID:5649; OMIM: 600514; Uniprot ID:RELN_HUMAN; ENSEMBL ID: ENSG00000189056; HGNC ID: 9957
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005576	TAS	-	extracellular region	-
GO:0005578	IEA	-	proteinaceous extracellular matrix	-
GO:0005615	ISS	-	extracellular space	-
GO:0005737	ISS	-	cytoplasm	-
GO:0005886	IEA	-	plasma membrane	-
GO:0030425	ISS	-	dendrite	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004712	ISS	-	protein serine/threonine/tyrosine kinase activity	-
GO:0008236	IEA	-	serine-type peptidase activity	-
GO:0046872	IEA	-	metal ion binding	-
GO:0070325	ISS	-	lipoprotein particle receptor binding	10571240
GO:0070326	ISS	-	very-low-density lipoprotein particle receptor binding	10571240

GO ID	Evidence	Qualifier	GO_term	References
GO:0000904	ISS	-	cell morphogenesis involved in differentiation	-
GO:0001764	ISS	-	neuron migration	-
GO:0006508	IEA	-	proteolysis	-
GO:0007155	IEA	-	cell adhesion	-
GO:0007411	ISS	-	axon guidance	-
GO:0007411	TAS	-	axon guidance	-
GO:0007417	ISS	-	central nervous system development	-
GO:0007420	ISS	-	brain development	-
GO:0007616	IEA	-	long-term memory	-
GO:0008306	IEA	-	associative learning	-
GO:0010001	ISS	-	glial cell differentiation	-
GO:0010976	ISS	-	positive regulation of neuron projection development	-
GO:0014068	IEA	-	positive regulation of phosphatidylinositol 3-kinase signaling	-
GO:0016358	IEA	-	dendrite development	-
GO:0018108	ISS	-	peptidyl-tyrosine phosphorylation	-
GO:0021511	ISS	-	spinal cord patterning	-
GO:0021517	IEA	-	ventral spinal cord development	-
GO:0021766	ISS	-	hippocampus development	-
GO:0021800	ISS	-	cerebral cortex tangential migration	-
GO:0021819	IEA	-	layer formation in cerebral cortex	-
GO:0032008	IEA	-	positive regulation of TOR signaling	-
GO:0032793	ISS	-	positive regulation of CREB transcription factor activity	-
GO:0035418	IEA	-	protein localization to synapse	-
GO:0038026	ISS	-	reelin-mediated signaling pathway	10571240
GO:0045860	ISS	-	positive regulation of protein kinase activity	-
GO:0048265	ISS	-	response to pain	-
GO:0050731	ISS	-	positive regulation of peptidyl-tyrosine phosphorylation	10571240
GO:0050795	ISS	-	regulation of behavior	-
GO:0050804	ISS	-	modulation of synaptic transmission	-
GO:0051057	ISS	-	positive regulation of small GTPase mediated signal transduction	-
GO:0051968	ISS	-	positive regulation of synaptic transmission, glutamatergic	-
GO:0060291	IEA	-	long-term synaptic potentiation	-
GO:0061003	ISS	-	positive regulation of dendritic spine morphogenesis	-
GO:0061098	ISS	-	positive regulation of protein tyrosine kinase activity	-
GO:0090129	ISS	-	positive regulation of synapse maturation	-
GO:0097114	IEA	-	NMDA glutamate receptor clustering	-
GO:0097119	IEA	-	postsynaptic density protein 95 clustering	-
GO:0097120	IEA	-	receptor localization to synapse	-
GO:0097477	IEA	-	lateral motor column neuron migration	-
GO:1900273	ISS	-	positive regulation of long-term synaptic potentiation	-
GO:1902078	IEA	-	positive regulation of lateral motor column neuron migration	-
GO:2000310	ISS	-	regulation of NMDA receptor activity	-
GO:2000463	ISS	-	positive regulation of excitatory postsynaptic potential	-
GO:2000969	ISS	-	positive regulation of AMPA receptor activity	-

Gene Symbol	Interactant	Interaction ID	References	Description
VLDLR	RELN	113277	10571241 12670700 12899622	Affinity Capture-Western; Reconstituted Complex
VLDLR	RELN	111630	10571241 12670700 12899622	Affinity Capture-Western; Reconstituted Complex
RELN	RELN	111630	12135781	Affinity Capture-Western
LRP8	RELN	113579	12670700 12899622	Affinity Capture-Western; Reconstituted Complex
LRP8	RELN	111630	12670700 12899622	Affinity Capture-Western; Reconstituted Complex

AutismKB 2.0

Annotation Details for RELN