AutismKB 2.0

Annotation Details for PRSS8


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Basic Information Top
Gene Symbol:PRSS8 ( CAP1,PROSTASIN )
Gene Full Name: protease, serine, 8
Band: 16p11.2
Quick LinksEntrez ID:5652; OMIM: 600823; Uniprot ID:PRSS8_HUMAN; ENSEMBL ID: ENSG00000052344; HGNC ID: 9491
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region10077646
GO:0005615IDA-extracellular space16502470
GO:0005886IDA-plasma membrane19911255
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO:0019897IBA-extrinsic component of plasma membrane-
GO:0046658IBA-anchored component of plasma membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004175TAS-endopeptidase activity-
GO:0004252IEA-serine-type endopeptidase activity-
GO:0005515IPI-protein binding19911255
GO:0008236TAS-serine-type peptidase activity8034638
GO:0017080IBA-sodium channel regulator activity-
GO ID Evidence Qualifier GO_term References
GO:0006508IEA-proteolysis-
GO:0010765IBA-positive regulation of sodium ion transport-
GO:0065009IEA-regulation of molecular function-
GO:0070268TAS-cornification-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1923810
  • Data Attributes: HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018