AutismKB 2.0

Annotation Details for PSMA3


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Basic Information Top
Gene Symbol:PSMA3 ( HC8,MGC12306,MGC32631,PSC3 )
Gene Full Name: proteasome (prosome, macropain) subunit, alpha type, 3
Band: 14q23.1
Quick LinksEntrez ID:5684; OMIM: 176843; Uniprot ID:PSA3_HUMAN; ENSEMBL ID: ENSG00000100567; HGNC ID: 9532
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000502IDA-proteasome complex17323924
GO:0005634IDA-nucleus21630459
GO:0005634TAS-nucleus16130169
GO:0005654TAS-nucleoplasm-
GO:0005737TAS-cytoplasm16130169
GO:0005829TAS-cytosol-
GO:0005839IDA-proteasome core complex19208651
GO:0019773IEA-proteasome core complex, alpha-subunit complex-
GO:0045202IEA-synapse-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004298IEA-threonine-type endopeptidase activity-
GO:0005515IPI-protein binding11146632
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016032IEA-viral process-
GO:0016579TAS-protein deubiquitination-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043488TAS-regulation of mRNA stability-
GO:0043687TAS-post-translational protein modification-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0052548IMP-regulation of endopeptidase activity26524591
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PSMA3CDKN1A11165711350925 Reconstituted Complex
PSMA3CDKN1A10746011350925 Reconstituted Complex
PSMA3CRYAB11165711341940 Affinity Capture-Western; Co-fractionation; Two-hybrid
PSMA3CRYAB10780011341940 Affinity Capture-Western; Co-fractionation; Two-hybrid
PSMA3EGR111165712379479 Reconstituted Complex; Two-hybrid
PSMA3EGR110827812379479 Reconstituted Complex; Two-hybrid
PSMA3PLK111165711205743 Affinity Capture-Western; Biochemical Activity
PSMA3PLK111136211205743 Affinity Capture-Western; Biochemical Activity
PSMA3PSMA11116559451443 Co-purification
PSMA3PSMA11116579451443 Co-purification
PSMA6PSMA31116579451443 16169070 Co-purification; Two-hybrid
PSMA6PSMA31116609451443 16169070 Co-purification; Two-hybrid
BAT2PSMA311165714667819 Two-hybrid
BAT2PSMA311364614667819 Two-hybrid
XRN2PSMA311165715231747 Two-hybrid
XRN2PSMA311648315231747 Two-hybrid
SNRPBPSMA311165716169070 Two-hybrid
SNRPBPSMA311251216169070 Two-hybrid
SNRPFPSMA311165716169070 Two-hybrid
SNRPFPSMA311252016169070 Two-hybrid
STX11PSMA311165716169070 Two-hybrid
STX11PSMA311422416169070 Two-hybrid
PSMD13PSMA311165717353931 Affinity Capture-MS
PSMD13PSMA311169117353931 Affinity Capture-MS
TRIB3PSMA311165718276110 Two-hybrid
TRIB3PSMA312175618276110 Two-hybrid
PSMD14PSMA311165719412159 Affinity Capture-Western
PSMD14PSMA311550819412159 Affinity Capture-Western
SLX1BPSMA311165719596235 Affinity Capture-MS
SLX1BPSMA312247919596235 Affinity Capture-MS
IKBKGPSMA311165720098747 Reconstituted Complex
IKBKGPSMA311408920098747 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104883
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050913-120'