AutismKB 2.0

Annotation Details for RAD18


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Basic Information Top
Gene Symbol:RAD18 ( RNF73 )
Gene Full Name: RAD18 homolog (S. cerevisiae)
Band: 3p25.3
Quick LinksEntrez ID:56852; OMIM: 605256; Uniprot ID:RAD18_HUMAN; ENSEMBL ID: ENSG00000070950; HGNC ID: 18278
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus15632077
GO:0005634NAS-nucleus10884424
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005657IDA-replication fork18363965
GO:0005737IEA-cytoplasm-
GO:0005813IDA-centrosome15632077
GO:0016604IDA-nuclear body-
GO:0035861IDA-site of double-strand break25931565
GO:0042405IDA-nuclear inclusion body22036607
GO:0097505IBA-Rad6-Rad18 complex-
GO ID Evidence Qualifier GO_term References
GO:0000403IDA-Y-form DNA binding18363965
GO:0003684NAS-damaged DNA binding10884424
GO:0005515IPI-protein binding19549727
GO:0031593IDA-polyubiquitin binding22742833
GO:0031625IPI-ubiquitin protein ligase binding10908344
GO:0032403IPI-protein complex binding25931565
GO:0042802IDA-identical protein binding25023518
GO:0043142IBA-single-stranded DNA-dependent ATPase activity-
GO:0046872IEA-metal ion binding-
GO:0061630IBA-ubiquitin protein ligase activity-
GO ID Evidence Qualifier GO_term References
GO:0006281NAS-DNA repair10884424
GO:0006301IBA-postreplication repair-
GO:0006513IBA-protein monoubiquitination-
GO:0006974IDA-cellular response to DNA damage stimulus22036607
GO:0009411IBA-response to UV-
GO:0016567TAS-protein ubiquitination-
GO:0042769TAS-DNA damage response, detection of DNA damage-
GO:0051865IDA-protein autoubiquitination25023518
GO:0051984IMP-positive regulation of chromosome segregation25931565
GO:0060548IDA-negative regulation of cell death22036607
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RAD18FANCD212121220967207 21355096 Affinity Capture-Western; Co-localization
RAD18FANCD210847420967207 21355096 Affinity Capture-Western; Co-localization
RAD18PCNA11114220675655 Biochemical Activity
RAD18PCNA12121220675655 Biochemical Activity
RAD18POLH12121216824193 Affinity Capture-MS; Affinity Capture-Western
RAD18POLH11142516824193 Affinity Capture-MS; Affinity Capture-Western
RAD18RAD5112121219396164 Affinity Capture-Western; Reconstituted Complex
RAD18RAD5111182519396164 Affinity Capture-Western; Reconstituted Complex
RAD18HLTF11248018316726 Affinity Capture-Western; Reconstituted Complex
RAD18HLTF12121218316726 Affinity Capture-Western; Reconstituted Complex
RAD18TP53BP112121219228710 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
RAD18TP53BP111301119228710 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
RAD18TSG10112121219549727 Two-hybrid
RAD18TSG10111310219549727 Two-hybrid
RAD18UBE2A11316710884424 10908344 19549727 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RAD18UBE2A12121210884424 10908344 19549727 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RAD18UBE2B11316810884424 10908344 19549727 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RAD18UBE2B12121210884424 10908344 19549727 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RAD18UBE2I11317719549727 Two-hybrid
RAD18UBE2I12121219549727 Two-hybrid
RAD18SRRM212121216159877 Affinity Capture-MS
RAD18SRRM211707116159877 Affinity Capture-MS
RAD18POLK11953216611994 Affinity Capture-Western
RAD18POLK12121216611994 Affinity Capture-Western
RAD18FANCI12051121355096 Co-localization
RAD18FANCI12121221355096 Co-localization
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1890476
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-745'