Annotation Details for WRNIP1

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Basic Information Top

Gene Symbol:	WRNIP1 ( FLJ22526,RP11-420G6.2,WHIP,bA420G6.2 )
Gene Full Name:	Werner helicase interacting protein 1
Band:	6p25.2
Quick Links	Entrez ID:56897; OMIM: 608196; Uniprot ID:WRIP1_HUMAN; ENSEMBL ID: ENSG00000124535; HGNC ID: 20876
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:5 results
Molecular Function:6 results
Biological Process:3 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0000784	IDA	colocalizes_with	nuclear chromosome, telomeric region	24270157
GO:0005634	IDA	-	nucleus	17888034
GO:0005634	ISS	-	nucleus	-
GO:0016020	IDA	-	membrane	19946888
GO:0048471	IDA	-	perinuclear region of cytoplasm	17888034

GO ID	Evidence	Qualifier	GO_term	References
GO:0003677	IEA	-	DNA binding	-
GO:0005515	IPI	-	protein binding	15670210
GO:0005524	IEA	-	ATP binding	-
GO:0016887	IMP	-	ATPase activity	15670210
GO:0042802	IPI	-	identical protein binding	15670210
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000731	IDA	-	DNA synthesis involved in DNA repair	15670210
GO:0006260	IEA	-	DNA replication	-
GO:0030174	IDA	-	regulation of DNA-dependent DNA replication initiation	15670210

Protein-Protein Interaction

BioGRID:12 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
WRNIP1	PIN1	111317	16055720	Affinity Capture-MS
WRNIP1	PIN1	121227	16055720	Affinity Capture-MS
WRNIP1	UBC	113164	18613717	Affinity Capture-MS
WRNIP1	UBC	121227	18613717	Affinity Capture-MS
WRNIP1	WRN	121227	11301316	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
WRNIP1	WRN	113323	11301316	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
WRNIP1	USP11	121227	19615732	Affinity Capture-Western
WRNIP1	USP11	113866	19615732	Affinity Capture-Western
WRNIP1	USP25	121227	19615732	Affinity Capture-MS
WRNIP1	USP25	118895	19615732	Affinity Capture-MS
OSBPL10	WRNIP1	121227	19615732	Affinity Capture-MS
OSBPL10	WRNIP1	125385	19615732	Affinity Capture-MS

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:1926153
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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