AutismKB 2.0

Annotation Details for TWSG1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:TWSG1 ( TSG )
Gene Full Name: twisted gastrulation homolog 1 (Drosophila)
Band: 18p11.22
Quick LinksEntrez ID:57045; OMIM: 605049; Uniprot ID:TWSG1_HUMAN; ENSEMBL ID: ENSG00000128791; HGNC ID: 12429
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615IEA-extracellular space-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding25416956
GO:0050431IDA-transforming growth factor beta binding17164348
GO ID Evidence Qualifier GO_term References
GO:0001503IEA-ossification-
GO:0001707IEA-mesoderm formation-
GO:0001818IDA-negative regulation of cytokine production17164348
GO:0007179IDA-transforming growth factor beta receptor signaling pathway17164348
GO:0007435IEA-salivary gland morphogenesis-
GO:0010862IDA-positive regulation of pathway-restricted SMAD protein phosphorylation17164348
GO:0030097IEA-hemopoiesis-
GO:0030154IEA-cell differentiation-
GO:0030509IEA-BMP signaling pathway-
GO:0030513IEA-positive regulation of BMP signaling pathway-
GO:0030514IEA-negative regulation of BMP signaling pathway-
GO:0030900IEA-forebrain development-
GO:0043010IEA-camera-type eye development-
GO:0045668IEA-negative regulation of osteoblast differentiation-
GO:2000515IDA-negative regulation of CD4-positive, alpha-beta T cell activation17164348
GO:2000562IDA-negative regulation of CD4-positive, alpha-beta T cell proliferation17164348
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TWSG1BMP412133811260715 Reconstituted Complex
TWSG1BMP410712011260715 Reconstituted Complex
TWSG1CHRD12133811260715 Reconstituted Complex
TWSG1CHRD11419811260715 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2137520
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010509-2'