AutismKB 2.0

Annotation Details for CASC5


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Basic Information Top
Gene Symbol:CASC5 ( AF15Q14,CT29,D40,KIAA1570,KNL1,hKNL-1,hSpc105 )
Gene Full Name: cancer susceptibility candidate 5
Band: 15q14
Quick LinksEntrez ID:57082; OMIM: 609173; Uniprot ID:CASC5_HUMAN; ENSEMBL ID: ENSG00000137812; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000777IEA-condensed chromosome kinetochore-
GO:0001669IDA-acrosomal vesicle15579588
GO:0005634IDA-nucleus10980622
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016604IDA-nuclear body-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15231748
GO ID Evidence Qualifier GO_term References
GO:0001675NAS-acrosome assembly15579588
GO:0007062TAS-sister chromatid cohesion-
GO:0008608IDA-attachment of spindle microtubules to kinetochore17981135
GO:0010923IDA-negative regulation of phosphatase activity19389623
GO:0034080TAS-CENP-A containing nucleosome assembly-
GO:0034501IDA-protein localization to kinetochore22331848
GO:0051301IEA-cell division-
GO:0071173IDA-spindle assembly checkpoint17981135
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MIS12CASC512135415371340 15502821 Affinity Capture-MS
MIS12CASC512247415371340 15502821 Affinity Capture-MS
DSN1CASC512304515502821 Affinity Capture-MS
DSN1CASC512135415502821 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1923714
  • Data Attributes: HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018