AutismKB 2.0

Annotation Details for PSMD3


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Basic Information Top
Gene Symbol:PSMD3 ( P58,RPN3,S3,TSTA2 )
Gene Full Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Band: 17q21.1
Quick LinksEntrez ID:5709; OMIM: NA; Uniprot ID:PSMD3_HUMAN; ENSEMBL ID: ENSG00000108344; HGNC ID: 9560
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000502IDA-proteasome complex17323924
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus21630459
GO:0005654TAS-nucleoplasm-
GO:0005829TAS-cytosol-
GO:0008541IBA-proteasome regulatory particle, lid subcomplex-
GO:0016020IDA-membrane19946888
GO:0022624ISS-proteasome accessory complex-
GO:0034774TAS-secretory granule lumen-
GO:0070062IDA-extracellular exosome19056867
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15147878
GO:0030234IEA-enzyme regulator activity-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006511IBA-ubiquitin-dependent protein catabolic process-
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016579TAS-protein deubiquitination-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043312TAS-neutrophil degranulation-
GO:0043488TAS-regulation of mRNA stability-
GO:0043687TAS-post-translational protein modification-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PSMD3BLM10711015829507 Two-hybrid
PSMD3BLM11168215829507 Two-hybrid
TRAF6PSMD311304114743216 Affinity Capture-MS
TRAF6PSMD311168214743216 Affinity Capture-MS
PTP4A3PSMD311632717353931 Affinity Capture-MS
PTP4A3PSMD311168217353931 Affinity Capture-MS
WDR8PSMD311906817353931 Affinity Capture-MS
WDR8PSMD311168217353931 Affinity Capture-MS
C20orf24PSMD312101517353931 Affinity Capture-MS
C20orf24PSMD311168217353931 Affinity Capture-MS
PSMD10PSMD311168817353931 Affinity Capture-MS
PSMD10PSMD311168217353931 Affinity Capture-MS
PSMD13PSMD311169117353931 Affinity Capture-MS
PSMD13PSMD311168217353931 Affinity Capture-MS
PAAF1PSMD312319117353931 Affinity Capture-MS
PAAF1PSMD311168217353931 Affinity Capture-MS
PSMD6PSMD311519517353931 Affinity Capture-MS
PSMD6PSMD311168217353931 Affinity Capture-MS
PSMD14PSMD311550819615732 Affinity Capture-MS
PSMD14PSMD311168219615732 Affinity Capture-MS
UCHL5PSMD311950919615732 Affinity Capture-MS
UCHL5PSMD311168219615732 Affinity Capture-MS
PSMD7PSMD311168519615732 Affinity Capture-MS
PSMD7PSMD311168219615732 Affinity Capture-MS
USP14PSMD311455119615732 Affinity Capture-MS
USP14PSMD311168219615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:98858
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1444'