AutismKB 2.0

Annotation Details for PSME1


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Basic Information Top
Gene Symbol:PSME1 ( IFI5111,MGC8628,PA28A,PA28alpha,REGalpha )
Gene Full Name: proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
Band: 14q12
Quick LinksEntrez ID:5720; OMIM: 600654; Uniprot ID:PSME1_HUMAN; ENSEMBL ID: ENSG00000092010; HGNC ID: 9568
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000502TAS-proteasome complex8811196
GO:0005654TAS-nucleoplasm-
GO:0005737TAS-cytoplasm16130169
GO:0005829TAS-cytosol-
GO:0008537IEA-proteasome activator complex-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16189514
GO:0061133IBA-endopeptidase activator activity-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0010950IBA-positive regulation of endopeptidase activity-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016579TAS-protein deubiquitination-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043488TAS-regulation of mRNA stability-
GO:0043687TAS-post-translational protein modification-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0061136IBA-regulation of proteasomal protein catabolic process-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
GO:2000045IBA-regulation of G1/S transition of mitotic cell cycle-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PSME1CHD310753216169070 Two-hybrid
PSME1CHD311169216169070 Two-hybrid
PSME1EMD11169212755701 Affinity Capture-Western; Two-hybrid
PSME1EMD10832512755701 Affinity Capture-Western; Two-hybrid
PSME1EIF611169216169070 Two-hybrid
PSME1EIF610989816169070 Two-hybrid
PSME1PFDN111169216169070 Two-hybrid
PSME1PFDN111122316169070 Two-hybrid
PSME2PSME11116928663520 16189514 Affinity Capture-Western; Two-hybrid
PSME2PSME11116938663520 16189514 Affinity Capture-Western; Two-hybrid
PSME1PSME11116929403698 16169070 Co-crystal Structure; Two-hybrid
TUBB2CPSME111565616169070 Two-hybrid
TUBB2CPSME111169216169070 Two-hybrid
USP22PSME111691416169070 Two-hybrid
USP22PSME111169216169070 Two-hybrid
VCLPSME111169216169070 Two-hybrid
VCLPSME111325716169070 Two-hybrid
VIMPSME111169216169070 Two-hybrid
VIMPSME111327216169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1096367
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-991110-17'