AutismKB 2.0

Annotation Details for PSME2


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Basic Information Top
Gene Symbol:PSME2 ( PA28B,PA28beta,REGbeta )
Gene Full Name: proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
Band: 14q12
Quick LinksEntrez ID:5721; OMIM: 602161; Uniprot ID:PSME2_HUMAN; ENSEMBL ID: ENSG00000100911; HGNC ID: 9569
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000502TAS-proteasome complex8811196
GO:0005654TAS-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO:0008537IEA-proteasome activator complex-
GO:0016020IDA-membrane19946888
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16189514
GO:0042802IPI-identical protein binding16189514
GO:0061133IBA-endopeptidase activator activity-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0000209TAS-protein polyubiquitination-
GO:0002223TAS-stimulatory C-type lectin receptor signaling pathway-
GO:0002479TAS-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-
GO:0006521TAS-regulation of cellular amino acid metabolic process-
GO:0010950IBA-positive regulation of endopeptidase activity-
GO:0010972TAS-negative regulation of G2/M transition of mitotic cell cycle-
GO:0016579TAS-protein deubiquitination-
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0031146TAS-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-
GO:0033209TAS-tumor necrosis factor-mediated signaling pathway-
GO:0038061TAS-NIK/NF-kappaB signaling-
GO:0038095TAS-Fc-epsilon receptor signaling pathway-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0043488TAS-regulation of mRNA stability-
GO:0043687TAS-post-translational protein modification-
GO:0050852TAS-T cell receptor signaling pathway-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0055085TAS-transmembrane transport-
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0061136IBA-regulation of proteasomal protein catabolic process-
GO:0061418TAS-regulation of transcription from RNA polymerase II promoter in response to hypoxia-
GO:0090090TAS-negative regulation of canonical Wnt signaling pathway-
GO:0090263TAS-positive regulation of canonical Wnt signaling pathway-
GO:2000045IBA-regulation of G1/S transition of mitotic cell cycle-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PSME2MGMT11169316226712 Affinity Capture-MS
PSME2MGMT11041116226712 Affinity Capture-MS
PSME2PSME11116928663520 16189514 Affinity Capture-Western; Two-hybrid
PSME2PSME11116938663520 16189514 Affinity Capture-Western; Two-hybrid
PSME2PSME211169316189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1096365
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-991110-16'