AutismKB 2.0

Annotation Details for PTBP1


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Basic Information Top
Gene Symbol:PTBP1 ( HNRNP-I,HNRNPI,HNRPI,MGC10830,MGC8461,PTB,PTB-1,PTB-T,PTB2,PTB3,PTB4,pPTB )
Gene Full Name: polypyrimidine tract binding protein 1
Band: 19p13.3
Quick LinksEntrez ID:5725; OMIM: 600693; Uniprot ID:PTBP1_HUMAN; ENSEMBL ID: ENSG00000011304; HGNC ID: 9583
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654TAS-nucleoplasm-
GO:0005730TAS-nucleolus1641332
GO:0016020IDA-membrane19946888
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding10653975
GO:0008187TAS-poly-pyrimidine tract binding1906036
GO:0036002IDA-pre-mRNA binding16260624
GO ID Evidence Qualifier GO_term References
GO:0000381IDA-regulation of alternative mRNA splicing, via spliceosome16260624
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006397TAS-mRNA processing1906036
GO:0008380TAS-RNA splicing1906036
GO:0008543TAS-fibroblast growth factor receptor signaling pathway-
GO:0016070TAS-RNA metabolic process-
GO:0033119IDA-negative regulation of RNA splicing18335065
GO:0048025IDA-negative regulation of mRNA splicing, via spliceosome15009664
GO:0051148IDA-negative regulation of muscle cell differentiation21518792
GO:0075522IMP-IRES-dependent viral translational initiation21518806
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTBP1APBB110681916055720 Affinity Capture-MS
PTBP1APBB111169716055720 Affinity Capture-MS
PTBP1HNRNPK10943110772858 Reconstituted Complex; Two-hybrid
PTBP1HNRNPK11169710772858 Reconstituted Complex; Two-hybrid
PTBP1HNRNPL1116979563502 10772858 Reconstituted Complex; Two-hybrid
PTBP1HNRNPL1094329563502 10772858 Reconstituted Complex; Two-hybrid
PTBP1PCBP211112710772858 Reconstituted Complex; Two-hybrid
PTBP1PCBP211169710772858 Reconstituted Complex; Two-hybrid
SFPQPTBP11123198449401 10653975 Affinity Capture-Western; Reconstituted Complex
SFPQPTBP11116978449401 10653975 Affinity Capture-Western; Reconstituted Complex
PTBP1PTBP11116979563502 10772858 16189514 Reconstituted Complex; Two-hybrid
SRRM1PTBP111169716159877 Affinity Capture-MS
SRRM1PTBP111554416159877 Affinity Capture-MS
CALCOCO2PTBP111553516189514 Two-hybrid
CALCOCO2PTBP111169716189514 Two-hybrid
SNRPAPTBP111251016189514 Two-hybrid
SNRPAPTBP111169716189514 Two-hybrid
SAP25PTBP194101816449650 Affinity Capture-MS
SAP25PTBP111169716449650 Affinity Capture-MS
SUMO1PTBP111318817549794 Affinity Capture-MS
SUMO1PTBP111169717549794 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97791
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9796'