AutismKB 2.0

Annotation Details for PTGDS


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Basic Information Top
Gene Symbol:PTGDS ( L-PGDS,LPGDS,PDS,PGD2,PGDS,PGDS2 )
Gene Full Name: prostaglandin D2 synthase 21kDa (brain)
Band: 9q34.3
Quick LinksEntrez ID:5730; OMIM: 176803; Uniprot ID:PTGDS_HUMAN; ENSEMBL ID: ENSG00000107317; HGNC ID: 9592
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IDA-extracellular region7692978
GO:0005615IDA-extracellular space19878301
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005791IDA-rough endoplasmic reticulum9065498
GO:0005794ISS-Golgi apparatus-
GO:0031965IEA-nuclear membrane-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0004667IDA-prostaglandin-D synthase activity20667974
GO:0004667ISS-prostaglandin-D synthase activity-
GO:0004667TAS-prostaglandin-D synthase activity-
GO:0005215ISS-transporter activity-
GO:0005501ISS-retinoid binding-
GO:0005504IDA-fatty acid binding20667974
GO:0005515IPI-protein binding25416956
GO ID Evidence Qualifier GO_term References
GO:0001516IDA-prostaglandin biosynthetic process20667974
GO:0001516ISS-prostaglandin biosynthetic process-
GO:0006810ISS-transport-
GO:0019371TAS-cyclooxygenase pathway-
GO:0045187ISS-regulation of circadian sleep/wake cycle, sleep-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTGDSEGFR11170220029029 PCA
PTGDSEGFR10827620029029 PCA
Gene Symbol Interactant Interaction ID References Description
PTGDSHK217176811068878 HKII interacts with PGDS. This interaction was modeled on a demonstrated interaction between rat HKII and human PGDS.
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PTGDSrs13306, rs3814500, rs4880179, rs6926 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:99261
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8436'