AutismKB 2.0

Annotation Details for PTGER4


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Basic Information Top
Gene Symbol:PTGER4 ( EP4,EP4R,MGC126583 )
Gene Full Name: prostaglandin E receptor 4 (subtype EP4)
Band: 5p13.1
Quick LinksEntrez ID:5734; OMIM: 601586; Uniprot ID:PE2R4_HUMAN; ENSEMBL ID: ENSG00000171522; HGNC ID: 9596
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0016021NAS-integral component of membrane8163486
GO ID Evidence Qualifier GO_term References
GO:0004957IDA-prostaglandin E receptor activity8163486
GO:0005515IPI-protein binding16424369
GO ID Evidence Qualifier GO_term References
GO:0006955IEP-immune response8862514
GO:0007188IDA-adenylate cyclase-modulating G-protein coupled receptor signaling pathway8163486
GO:0007254ISS-JNK cascade-
GO:0009612IEP-response to mechanical stimulus21723865
GO:0030278IEA-regulation of ossification-
GO:0032496IEA-response to lipopolysaccharide-
GO:0033624IDA-negative regulation of integrin activation21681739
GO:0042093ISS-T-helper cell differentiation-
GO:0050710ISS-negative regulation of cytokine secretion-
GO:0050715ISS-positive regulation of cytokine secretion-
GO:0050728IDA-negative regulation of inflammatory response16424369
GO:0050729ISS-positive regulation of inflammatory response-
GO:0051492ISS-regulation of stress fiber assembly-
GO:0060348ISS-bone development-
GO:0070371ISS-ERK1 and ERK2 cascade-
GO:0071260ISS-cellular response to mechanical stimulus-
GO:0071380IBA-cellular response to prostaglandin E stimulus-
GO:2000420IDA-negative regulation of eosinophil extravasation21681739
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104311
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060222-1'