AutismKB 2.0

Annotation Details for PTGS1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTGS1 ( COX1,COX3,PCOX1,PGG/HS,PGHS-1,PGHS1,PHS1,PTGHS )
Gene Full Name: prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Band: 9q33.2
Quick LinksEntrez ID:5742; OMIM: 176805; Uniprot ID:PGH1_HUMAN; ENSEMBL ID: ENSG00000095303; HGNC ID: 9604
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001750IEA-photoreceptor outer segment-
GO:0005634ISS-nucleus-
GO:0005737IDA-cytoplasm12355421
GO:0005737ISS-cytoplasm-
GO:0005789TAS-endoplasmic reticulum membrane-
GO:0005794IDA-Golgi apparatus-
GO:0031090IEA-organelle membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0043231ISS-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome18570454
GO ID Evidence Qualifier GO_term References
GO:0004601TAS-peroxidase activity-
GO:0004666IDA-prostaglandin-endoperoxide synthase activity1380156
GO:0004666TAS-prostaglandin-endoperoxide synthase activity-
GO:0020037IEA-heme binding-
GO:0046872IEA-metal ion binding-
GO:0051213IEA-dioxygenase activity-
GO ID Evidence Qualifier GO_term References
GO:0001516ISS-prostaglandin biosynthetic process-
GO:0006629NAS-lipid metabolic process1907252
GO:0006805TAS-xenobiotic metabolic process-
GO:0006954IEA-inflammatory response-
GO:0006979IEA-response to oxidative stress-
GO:0008217ISS-regulation of blood pressure-
GO:0019371IDA-cyclooxygenase pathway1380156
GO:0019371TAS-cyclooxygenase pathway-
GO:0042127IEA-regulation of cell proliferation-
GO:0055114IEA-oxidation-reduction process-
GO:0098869IEA-cellular oxidant detoxification-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTGS1NUCB11109788643612 Two-hybrid
PTGS1NUCB11117148643612 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
PTGS1rs4836887 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:97797
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-020530-1'