AutismKB 2.0

Annotation Details for BIRC6


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Basic Information Top
Gene Symbol:BIRC6 ( APOLLON,BRUCE,FLJ13726,FLJ13786,KIAA1289 )
Gene Full Name: baculoviral IAP repeat-containing 6
Band: 2p22.3
Quick LinksEntrez ID:57448; OMIM: 605638; Uniprot ID:BIRC6_HUMAN; ENSEMBL ID: ENSG00000115760; HGNC ID: 13516
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000922IDA-spindle pole18329369
GO:0005768IDA-endosome18329369
GO:0005794IDA-Golgi apparatus-
GO:0005802IDA-trans-Golgi network18329369
GO:0005815IDA-microtubule organizing center18329369
GO:0016020IDA-membrane19946888
GO:0030496IDA-midbody18329369
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0004842IDA-ubiquitin-protein transferase activity15200957
GO:0004869IMP-cysteine-type endopeptidase inhibitor activity15200957
GO:0005515IPI-protein binding14765125
GO:0061631IEA-ubiquitin conjugating enzyme activity-
GO ID Evidence Qualifier GO_term References
GO:0006468TAS-protein phosphorylation18329369
GO:0006915IEA-apoptotic process-
GO:0007049IEA-cell cycle-
GO:0008284IEA-positive regulation of cell proliferation-
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0016567TAS-protein ubiquitination18329369
GO:0032465IMP-regulation of cytokinesis18329369
GO:0042127TAS-regulation of cell proliferation18414036
GO:0043066IMP-negative regulation of apoptotic process15200957
GO:0043066TAS-negative regulation of apoptotic process10544019
GO:0051301IEA-cell division-
GO:0060711IEA-labyrinthine layer development-
GO:0060712IEA-spongiotrophoblast layer development-
GO:2001237IMP-negative regulation of extrinsic apoptotic signaling pathway14765125
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BIRC6USP811455518329369 Affinity Capture-Western
BIRC6USP812152118329369 Affinity Capture-Western
BIRC6KIF2311487318329369 Affinity Capture-Western
BIRC6KIF2312152118329369 Affinity Capture-Western
BIRC6RNF4112152115314180 Affinity Capture-MS
BIRC6RNF4111548815314180 Affinity Capture-MS
Gene Symbol Interactant Interaction ID References Description
BIRC6CASP618057815200957 BRUCE interacts with Casp-6. This interaction was modeled on a demonstrated interaction between mouse BRUCE and human Casp-6.
BIRC6CASP718058015200957 BRUCE interacts with Casp-7. This interaction was modeled on a demonstrated interaction between mouse BRUCE and human Casp-7.
BIRC6CASP918058415200957 BRUCE interacts with Casp-9. This interaction was modeled on a demonstrated interaction between mouse BRUCE and human Casp-9.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1276108
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-091202-7'