Annotation Details for MKL2
Basic Information Top
| Gene Symbol: | MKL2 ( DKFZp686J1745,FLJ31823,FLJ45623,MRTF-B,NPD001 ) |
|---|---|
| Gene Full Name: | MKL/myocardin-like 2 |
| Band: | 16p13.12 |
| Quick Links | Entrez ID:57496; OMIM: 609463; Uniprot ID:MKL2_HUMAN; ENSEMBL ID: ENSG00000186260; HGNC ID: 29819 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005634 | IBA | - | nucleus | - |
| GO:0005634 | IC | - | nucleus | 14565952 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0001105 | IBA | - | RNA polymerase II transcription coactivator activity | - |
| GO:0003713 | IDA | - | transcription coactivator activity | 14565952 |
| GO:0005515 | IPI | - | protein binding | 12397177 |
| GO:0045296 | IDA | - | cadherin binding | 25468996 |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0006366 | IEA | - | transcription from RNA polymerase II promoter | - |
| GO:0007517 | IEA | - | muscle organ development | - |
| GO:0045844 | IDA | - | positive regulation of striated muscle tissue development | 14565952 |
| GO:0045944 | IDA | - | positive regulation of transcription from RNA polymerase II promoter | 14565952 |
| GO:0051145 | IBA | - | smooth muscle cell differentiation | - |
| Gene Symbol | Interactant | Interaction ID | References | Description |
|---|---|---|---|---|
| MKL2 | SRF | 112600 | 14565952 | Affinity Capture-Western |
| MKL2 | SRF | 121563 | 14565952 | Affinity Capture-Western |
| MKL2 | KDM3A | 120927 | 17991879 | Reconstituted Complex |
| MKL2 | KDM3A | 121563 | 17991879 | Reconstituted Complex |
| MKL2 | MKL2 | 121563 | 14565952 | Affinity Capture-Western |
| MKL1 | MKL2 | 121642 | 14565952 | Affinity Capture-Western |
| MKL1 | MKL2 | 121563 | 14565952 | Affinity Capture-Western |
| No data |
| No data |
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