AutismKB 2.0

Annotation Details for SRGAP1


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Basic Information Top
Gene Symbol:SRGAP1 ( ARHGAP13,FLJ22166,KIAA1304 )
Gene Full Name: SLIT-ROBO Rho GTPase activating protein 1
Band: 12q14.2
Quick LinksEntrez ID:57522; OMIM: 606523; Uniprot ID:SRGP1_HUMAN; ENSEMBL ID: ENSG00000196935; HGNC ID: 17382
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005096IBA-GTPase activator activity-
GO:0005096TAS-GTPase activator activity-
GO:0005515IPI-protein binding17500595
GO:0048365IBA-Rac GTPase binding-
GO ID Evidence Qualifier GO_term References
GO:0007165IEA-signal transduction-
GO:0030336IBA-negative regulation of cell migration-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2152936
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018