AutismKB 2.0

Annotation Details for PTK6


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Basic Information Top
Gene Symbol:PTK6 ( BRK,FLJ42088 )
Gene Full Name: PTK6 protein tyrosine kinase 6
Band: 20q13.33
Quick LinksEntrez ID:5753; OMIM: 602004; Uniprot ID:PTK6_HUMAN; ENSEMBL ID: ENSG00000101213; HGNC ID: 9617
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001726IDA-ruffle15572663
GO:0005634IDA-nucleus10913193
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm15572663
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005886IDA-plasma membrane-
GO:0016604IDA-nuclear body-
GO:0031234IBA-extrinsic component of cytoplasmic side of plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0004713EXP-protein tyrosine kinase activity16568091
GO:0004713TAS-protein tyrosine kinase activity-
GO:0004715IDA-non-membrane spanning protein tyrosine kinase activity10913193
GO:0005102IBA-receptor binding-
GO:0005515IPI-protein binding10913193
GO:0005524IEA-ATP binding-
GO:0042802IPI-identical protein binding15056653
GO ID Evidence Qualifier GO_term References
GO:0006468TAS-protein phosphorylation8036022
GO:0007169IBA-transmembrane receptor protein tyrosine kinase signaling pathway-
GO:0007260IDA-tyrosine phosphorylation of STAT protein16568091
GO:0009968TAS-negative regulation of signal transduction-
GO:0010976IMP-positive regulation of neuron projection development17910947
GO:0016477IDA-cell migration15572663
GO:0038083IBA-peptidyl-tyrosine autophosphorylation-
GO:0038128TAS-ERBB2 signaling pathway-
GO:0042127IBA-regulation of cell proliferation-
GO:0045087IBA-innate immune response-
GO:0045742TAS-positive regulation of epidermal growth factor receptor signaling pathway-
GO:0045787TAS-positive regulation of cell cycle-
GO:0045926IEA-negative regulation of growth-
GO:0046777IMP-protein autophosphorylation12121988
GO:0060575IEA-intestinal epithelial cell differentiation-
GO:0061099IDA-negative regulation of protein tyrosine kinase activity15539407
GO:0071300IMP-cellular response to retinoic acid17910947
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTK6EGFR1117208940083 Affinity Capture-Western
PTK6EGFR1082768940083 Affinity Capture-Western
PTK6ERBB311172011114724 Affinity Capture-Western
PTK6ERBB310837711114724 Affinity Capture-Western
KHDRBS1PTK611590010913193 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
KHDRBS1PTK611172010913193 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
STAP2PTK611172010980601 Reconstituted Complex; Two-hybrid
STAP2PTK612075910980601 Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99683
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060929-1150'