Annotation Details for LRRC7

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Basic Information Top

Gene Symbol:	LRRC7 ( DKFZp686I1147,KIAA1365,MGC144918 )
Gene Full Name:	leucine rich repeat containing 7
Band:	1p31.1
Quick Links	Entrez ID:57554; OMIM: NA; Uniprot ID:LRRC7_HUMAN; ENSEMBL ID: ENSG00000033122; HGNC ID: 18531
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:8 results
Molecular Function:1 results
Biological Process:3 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005576	TAS	-	extracellular region	-
GO:0005737	IBA	-	cytoplasm	-
GO:0005886	IBA	-	plasma membrane	-
GO:0014069	IEA	-	postsynaptic density	-
GO:0030054	IEA	-	cell junction	-
GO:0035580	TAS	-	specific granule lumen	-
GO:0043005	IBA	-	neuron projection	-
GO:0045211	IEA	-	postsynaptic membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007165	IBA	-	signal transduction	-
GO:0010976	IBA	-	positive regulation of neuron projection development	-
GO:0043312	TAS	-	neutrophil degranulation	-

Protein-Protein Interaction

BioGRID:10 results
BIND:1 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
LRRC7	CDH2	107435	11729199	Affinity Capture-Western; Reconstituted Complex
LRRC7	CDH2	121610	11729199	Affinity Capture-Western; Reconstituted Complex
LRRC7	CTNND2	121610	11729199	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRRC7	CTNND2	107882	11729199	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRRC7	DLG4	121610	12390249	Affinity Capture-Western
LRRC7	DLG4	108086	12390249	Affinity Capture-Western
LRRC7	SSSCA1	121610	17353931	Affinity Capture-MS
LRRC7	SSSCA1	115788	17353931	Affinity Capture-MS
LRRC7	CNKSR2	121610	12390249	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LRRC7	CNKSR2	116534	12390249	Affinity Capture-Western; Reconstituted Complex; Two-hybrid

Gene Symbol	Interactant	Interaction ID	References	Description
LRRC7	ACTN4	258908	11160423	LRRC7 (Densin-180) interacts with ACTN4 (alpha-Actinin 4). This interaction was modeled on a demonstrated interaction between rat LRCC7 and human ACTN4.

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:1 results

MGI ID: MGI:2676665
Data Attributes: MGI curated and HomoloGene calculated