AutismKB 2.0

Annotation Details for TWF1


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Basic Information Top
Gene Symbol:TWF1 ( A6,MGC23788,MGC41876,PTK9 )
Gene Full Name: twinfilin, actin-binding protein, homolog 1 (Drosophila)
Band: 12q12
Quick LinksEntrez ID:5756; OMIM: 610932; Uniprot ID:TWF1_HUMAN; ENSEMBL ID: ENSG00000151239; HGNC ID: 9620
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829IDA-cytosol-
GO:0005911ISS-cell-cell junction12807912
GO:0005925IDA-focal adhesion21423176
GO:0015629ISS-actin cytoskeleton-
GO:0030016ISS-myofibril18837697
GO:0030175ISS-filopodium12807912
GO:0032587ISScolocalizes_withruffle membrane12807912
GO:0048471ISS-perinuclear region of cytoplasm12807912
GO ID Evidence Qualifier GO_term References
GO:0003785ISS-actin monomer binding12807912
GO:0004713IDANOTprotein tyrosine kinase activity10406962
GO:0005524IDA-ATP binding10406962
GO:0005546ISS-phosphatidylinositol-4,5-bisphosphate binding12807912
GO:0032403IEA-protein complex binding-
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0010613IEA-positive regulation of cardiac muscle hypertrophy-
GO:0030837ISS-negative regulation of actin filament polymerization12807912
GO:0042989ISS-sequestering of actin monomers18837697
GO:0043538IDA-regulation of actin phosphorylation10406962
GO:0051016IEA-barbed-end actin filament capping-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1100520
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-4402'