Annotation Details for PREX1
Basic Information Top
| Gene Symbol: | PREX1 ( KIAA1415,P-REX1 ) |
|---|---|
| Gene Full Name: | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
| Band: | 20q13.13 |
| Quick Links | Entrez ID:57580; OMIM: 606905; Uniprot ID:PREX1_HUMAN; ENSEMBL ID: ENSG00000124126; HGNC ID: 32594 |
| Relate to Another Database: | SFARIGene; denovo-db |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005829 | IDA | - | cytosol | 11955434 |
| GO:0005829 | TAS | - | cytosol | - |
| GO:0005886 | TAS | - | plasma membrane | 12123595 |
| GO:0030426 | IEA | - | growth cone | - |
| GO:0043198 | IEA | - | dendritic shaft | - |
| GO:0048471 | IEA | - | perinuclear region of cytoplasm | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0005085 | TAS | - | guanyl-nucleotide exchange factor activity | - |
| GO:0005089 | TAS | - | Rho guanyl-nucleotide exchange factor activity | 12123595 |
| GO:0005096 | TAS | - | GTPase activator activity | 12123595 |
| GO:0005515 | IPI | - | protein binding | 17565979 |
| GO:0005543 | IDA | - | phospholipid binding | 11955434 |
| GO:0019899 | TAS | - | enzyme binding | 12123595 |
| GO:0030676 | IBA | - | Rac guanyl-nucleotide exchange factor activity | - |
| GO ID | Evidence | Qualifier | GO_term | References |
|---|---|---|---|---|
| GO:0006469 | IBA | - | negative regulation of protein kinase activity | - |
| GO:0006801 | TAS | - | superoxide metabolic process | 12123595 |
| GO:0007186 | IBA | - | G-protein coupled receptor signaling pathway | - |
| GO:0030041 | TAS | - | actin filament polymerization | 12123595 |
| GO:0030217 | IEA | - | T cell differentiation | - |
| GO:0030335 | IEA | - | positive regulation of cell migration | - |
| GO:0030593 | IEA | - | neutrophil chemotaxis | - |
| GO:0030833 | IEA | - | regulation of actin filament polymerization | - |
| GO:0032007 | IBA | - | negative regulation of TOR signaling | - |
| GO:0035023 | IEA | - | regulation of Rho protein signal transduction | - |
| GO:0035556 | IEA | - | intracellular signal transduction | - |
| GO:0042119 | TAS | - | neutrophil activation | 12123595 |
| GO:0043065 | TAS | - | positive regulation of apoptotic process | - |
| GO:0043547 | IEA | - | positive regulation of GTPase activity | - |
| GO:0050773 | IEA | - | regulation of dendrite development | - |
| GO:0051056 | TAS | - | regulation of small GTPase mediated signal transduction | - |
| GO:1900026 | IEA | - | positive regulation of substrate adhesion-dependent cell spreading | - |
AlzGene, PDGene and SZGene