AutismKB 2.0

Annotation Details for MKL1


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Basic Information Top
Gene Symbol:MKL1 ( BSAC,MAL,MRTF-A )
Gene Full Name: megakaryoblastic leukemia (translocation) 1
Band: 22q13.1-q13.2
Quick LinksEntrez ID:57591; OMIM: 606078; Uniprot ID:MKL1_HUMAN; ENSEMBL ID: ENSG00000196588; HGNC ID: 14334
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus14970199
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm14970199
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0001105IBA-RNA polymerase II transcription coactivator activity-
GO:0003713ISS-transcription coactivator activity-
GO:0003779IDA-actin binding24440334
GO:0003785ISS-actin monomer binding-
GO:0005515IPI-protein binding12397177
GO:0043522IPI-leucine zipper domain binding14970199
GO ID Evidence Qualifier GO_term References
GO:0006366IEA-transcription from RNA polymerase II promoter-
GO:0010735IDA-positive regulation of transcription via serum response element binding24440334
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter14970199
GO:0051145IMP-smooth muscle cell differentiation14970199
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MKL1SRF12164214565952 Affinity Capture-Western
MKL1SRF11260014565952 Affinity Capture-Western
MKL1SSRP112164218036521 Affinity Capture-Western
MKL1SSRP111262718036521 Affinity Capture-Western
MKL1SUPT16H12164218036521 Affinity Capture-Western
MKL1SUPT16H11636718036521 Affinity Capture-Western
MKL1KDM3A12164217991879 Reconstituted Complex
MKL1KDM3A12092717991879 Reconstituted Complex
MKL1MKL212164214565952 Affinity Capture-Western
MKL1MKL212156314565952 Affinity Capture-Western
MYOCDMKL112164214970199 Reconstituted Complex
MYOCDMKL112504414970199 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2384495
  • Data Attributes: MGI curated and HomoloGene calculated
No data