Gene Symbol:	SPTBN4 ( KIAA1642,QV,SPNB4,SPTBN3 )
Gene Full Name:	spectrin, beta, non-erythrocytic 4
Band:	19q13.13
Quick Links	Entrez ID:57731; OMIM: 606214; Uniprot ID:SPTN4_HUMAN; ENSEMBL ID: ENSG00000160460; HGNC ID: 14896
Relate to Another Database:	SFARIGene; denovo-db

GO ID	Evidence	Qualifier	GO_term	References
GO:0005737	IDA	-	cytoplasm	11294830
GO:0005737	ISS	-	cytoplasm	-
GO:0005829	TAS	-	cytosol	-
GO:0005886	ISS	-	plasma membrane	-
GO:0005912	ISS	-	adherens junction	-
GO:0008091	IDA	-	spectrin	11086001
GO:0008091	ISS	-	spectrin	-
GO:0016020	IDA	-	membrane	11086001
GO:0016363	IDA	-	nuclear matrix	11294830
GO:0016363	ISS	-	nuclear matrix	-
GO:0016605	IDA	-	PML body	11294830
GO:0016605	ISS	-	PML body	-
GO:0033268	ISS	-	node of Ranvier	-
GO:0033270	IEA	-	paranode region of axon	-
GO:0043025	ISS	-	neuronal cell body	-
GO:0043194	ISS	-	axon initial segment	-
GO:0043203	ISS	-	axon hillock	-
GO:0070062	IDA	-	extracellular exosome	23533145
GO:0070852	ISS	-	cell body fiber	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0003779	ISS	-	actin binding	-
GO:0003779	TAS	-	actin binding	11086001
GO:0005088	TAS	-	Ras guanyl-nucleotide exchange factor activity	-
GO:0005200	TAS	-	structural constituent of cytoskeleton	11294830
GO:0005515	IPI	-	protein binding	11086001
GO:0005543	IEA	-	phospholipid binding	-
GO:0019902	IPI	-	phosphatase binding	11086001
GO:0030506	IDA	-	ankyrin binding	11294830
GO:0030506	ISS	-	ankyrin binding	-
GO:0030507	ISS	-	spectrin binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0000165	TAS	-	MAPK cascade	-
GO:0002028	ISS	-	regulation of sodium ion transport	-
GO:0006888	TAS	-	ER to Golgi vesicle-mediated transport	-
GO:0007016	TAS	-	cytoskeletal anchoring at plasma membrane	11086001
GO:0007409	ISS	-	axonogenesis	-
GO:0007411	TAS	-	axon guidance	-
GO:0007605	ISS	-	sensory perception of sound	-
GO:0007628	ISS	-	adult walking behavior	-
GO:0009566	IEA	-	fertilization	-
GO:0010459	ISS	-	negative regulation of heart rate	-
GO:0016192	TAS	-	vesicle-mediated transport	11294830
GO:0019226	ISS	-	transmission of nerve impulse	-
GO:0021952	ISS	-	central nervous system projection neuron axonogenesis	-
GO:0033135	ISS	-	regulation of peptidyl-serine phosphorylation	-
GO:0040018	IEA	-	positive regulation of multicellular organism growth	-
GO:0043547	IEA	-	positive regulation of GTPase activity	-
GO:0045162	ISS	-	clustering of voltage-gated sodium channels	-
GO:0051693	IEA	-	actin filament capping	-
GO:0061337	ISS	-	cardiac conduction	-
GO:0090002	ISS	-	establishment of protein localization to plasma membrane	-

Gene Symbol	Interactant	Interaction ID	References	Description
SPTBN4	ANK3	121751	11807096	Affinity Capture-Western
SPTBN4	ANK3	106785	11807096	Affinity Capture-Western
SPTBN4	PTPRN	121751	11086001	Affinity Capture-Western; Two-hybrid
SPTBN4	PTPRN	111762	11086001	Affinity Capture-Western; Two-hybrid
SPTBN4	PTPRN2	121751	11086001	Two-hybrid
SPTBN4	PTPRN2	111763	11086001	Two-hybrid
SPTBN4	DISC1	118061	12812986	Affinity Capture-Western; Two-hybrid
SPTBN4	DISC1	121751	12812986	Affinity Capture-Western; Two-hybrid

AutismKB 2.0

Annotation Details for SPTBN4