AutismKB 2.0

Annotation Details for PTPN7


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Basic Information Top
Gene Symbol:PTPN7 ( BPTP-4,HEPTP,LC-PTP,LPTP,PTPNI )
Gene Full Name: protein tyrosine phosphatase, non-receptor type 7
Band: 1q32.1
Quick LinksEntrez ID:5778; OMIM: 176889; Uniprot ID:PTN7_HUMAN; ENSEMBL ID: ENSG00000143851; HGNC ID: 9659
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10940933
GO:0005829IDA-cytosol10940933
GO:0005856IEA-cytoskeleton-
GO:0009898IDA-cytoplasmic side of plasma membrane10940933
GO ID Evidence Qualifier GO_term References
GO:0004725IEA-protein tyrosine phosphatase activity-
GO:0005515IPI-protein binding10415025
GO ID Evidence Qualifier GO_term References
GO:0006470TAS-protein dephosphorylation1530918
GO:0035335IEA-peptidyl-tyrosine dephosphorylation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPN7MAPK111174310206983 10702794 Affinity Capture-Western; Biochemical Activity
PTPN7MAPK111158010206983 10702794 Affinity Capture-Western; Biochemical Activity
PTPN7MAPK311174310206983 10559944 10702794 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
PTPN7MAPK311158110206983 10559944 10702794 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2156893
  • Data Attributes: HomoloGene calculated
No data
No data

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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018