AutismKB 2.0

Annotation Details for PTPN14


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Basic Information Top
Gene Symbol:PTPN14 ( MGC126803,PEZ,PTP36 )
Gene Full Name: protein tyrosine phosphatase, non-receptor type 14
Band: 1q32.3-q41
Quick LinksEntrez ID:5784; OMIM: 603155; Uniprot ID:PTN14_HUMAN; ENSEMBL ID: ENSG00000152104; HGNC ID: 9647
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10934049
GO:0005654IDA-nucleoplasm-
GO:0005737IDA-cytoplasm10934049
GO:0005856IEA-cytoskeleton-
GO ID Evidence Qualifier GO_term References
GO:0003712IMP-transcription cofactor activity22525271
GO:0004725IMP-protein tyrosine phosphatase activity22525271
GO:0005515IPI-protein binding22525271
GO:0030971IPI-receptor tyrosine kinase binding20826270
GO ID Evidence Qualifier GO_term References
GO:0001946IMP-lymphangiogenesis20826270
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0006470TAS-protein dephosphorylation7733990
GO:0008285IMP-negative regulation of cell proliferation22948661
GO:0035335IEA-peptidyl-tyrosine dephosphorylation-
GO:0046825IDA-regulation of protein export from nucleus22948661
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPN14CTNNA111174812808048 Affinity Capture-MS
PTPN14CTNNA110787612808048 Affinity Capture-MS
PTPN14CTNNB111174812808048 Affinity Capture-MS; Affinity Capture-Western
PTPN14CTNNB110788012808048 Affinity Capture-MS; Affinity Capture-Western
PTPN14JUP10993112808048 Affinity Capture-MS
PTPN14JUP11174812808048 Affinity Capture-MS
TJP1PTPN1411174812808048 Affinity Capture-MS
TJP1PTPN1411293712808048 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:102467
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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