AutismKB 2.0

Annotation Details for PTPRJ


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTPRJ ( CD148,DEP1,HPTPeta,R-PTP-ETA,SCC1 )
Gene Full Name: protein tyrosine phosphatase, receptor type, J
Band: 11p11.2
Quick LinksEntrez ID:5795; OMIM: 600925; Uniprot ID:PTPRJ_HUMAN; ENSEMBL ID: ENSG00000149177; HGNC ID: 9673
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001772IDA-immunological synapse12913111
GO:0005886IDA-plasma membrane9531590
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7937872
GO:0005911IDA-cell-cell junction12370829
GO:0009986IDA-cell surface12913111
GO:0032587IEA-ruffle membrane-
GO:0035579TAS-specific granule membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0004725IDA-protein tyrosine phosphatase activity9531590
GO:0004725IMP-protein tyrosine phosphatase activity9780142
GO:0004725TAS-protein tyrosine phosphatase activity-
GO:0005161IPI-platelet-derived growth factor receptor binding10821867
GO:0005515IPI-protein binding10821867
GO:0008013IPI-beta-catenin binding12370829
GO:0016791IDA-phosphatase activity12062403
GO:0016791IMP-phosphatase activity11259588
GO:0019901IPI-protein kinase binding19332538
GO:0045295IPI-gamma-catenin binding12370829
GO:0051019IPI-mitogen-activated protein kinase binding19494114
GO:0070097IPI-delta-catenin binding12370829
GO ID Evidence Qualifier GO_term References
GO:0008285IDA-negative regulation of cell proliferation14709717
GO:0010642IDA-negative regulation of platelet-derived growth factor receptor signaling pathway14709717
GO:0030155IMP-regulation of cell adhesion12370829
GO:0030308IDA-negative regulation of cell growth14709717
GO:0030336IDA-negative regulation of cell migration16682945
GO:0035335IDA-peptidyl-tyrosine dephosphorylation9531590
GO:0035335IMP-peptidyl-tyrosine dephosphorylation9780142
GO:0042059IMP-negative regulation of epidermal growth factor receptor signaling pathway19836242
GO:0043116IDA-negative regulation of vascular permeability19332538
GO:0043312TAS-neutrophil degranulation-
GO:0043407IDA-negative regulation of MAP kinase activity19494114
GO:0045785IMP-positive regulation of cell adhesion21091576
GO:0048008IMP-platelet-derived growth factor receptor signaling pathway21091576
GO:0050852TAS-T cell receptor signaling pathway-
GO:0050860IDA-negative regulation of T cell receptor signaling pathway12913111
GO:0050860IMP-negative regulation of T cell receptor signaling pathway9780142
GO:0050918IDA-positive chemotaxis14709717
GO:0051894IMP-positive regulation of focal adhesion assembly21091576
GO:0051897IMP-positive regulation of protein kinase B signaling18936167
GO:0051898IMP-negative regulation of protein kinase B signaling19922411
GO:0060242NAS-contact inhibition7937872
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPRJCTNNB110788012370829 Affinity Capture-Western
PTPRJCTNNB111175912370829 Affinity Capture-Western
PTPRJCTNND110788112370829 Affinity Capture-Western; Biochemical Activity
PTPRJCTNND111175912370829 Affinity Capture-Western; Biochemical Activity
PTPRJPLCG111135111259588 Biochemical Activity
PTPRJPLCG111175911259588 Biochemical Activity
LATPTPRJ11797111259588 Biochemical Activity
LATPTPRJ11175911259588 Biochemical Activity
SDCBPPTPRJ11175912403354 Two-hybrid
SDCBPPTPRJ11228712403354 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104574
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8301'