AutismKB 2.0

Annotation Details for PTPRK


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Basic Information Top
Gene Symbol:PTPRK ( DKFZp686C2268,DKFZp779N1045,R-PTP-kappa )
Gene Full Name: protein tyrosine phosphatase, receptor type, K
Band: 6q22.33
Quick LinksEntrez ID:5796; OMIM: 602545; Uniprot ID:PTPRK_HUMAN; ENSEMBL ID: ENSG00000152894; HGNC ID: 9674
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001750IEA-photoreceptor outer segment-
GO:0005886IDA-plasma membrane-
GO:0005887NAS-integral component of plasma membrane9047348
GO:0005911IDA-cell-cell junction8663237
GO:0005912IEA-adherens junction-
GO:0009986IDA-cell surface18276111
GO:0016021NAS-integral component of membrane9047348
GO:0030054IDA-cell junction-
GO:0030424IEA-axon-
GO:0030425IEA-dendrite-
GO:0031256IDA-leading edge membrane15899872
GO:0043025IEA-neuronal cell body-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0004725IDA-protein tyrosine phosphatase activity8663237
GO:0005001NAS-transmembrane receptor protein tyrosine phosphatase activity9047348
GO:0005515IPI-protein binding15899872
GO:0008013IPI-beta-catenin binding8663237
GO:0019901IPI-protein kinase binding15899872
GO:0045295IPI-gamma-catenin binding8663237
GO ID Evidence Qualifier GO_term References
GO:0006470IDA-protein dephosphorylation16263724
GO:0007155IMP-cell adhesion15899872
GO:0007165IDA-signal transduction16849327
GO:0007179IDA-transforming growth factor beta receptor signaling pathway15899872
GO:0008285IDA-negative regulation of cell proliferation15899872
GO:0010839IDA-negative regulation of keratinocyte proliferation16263724
GO:0016477IMP-cell migration15899872
GO:0030336IDA-negative regulation of cell migration18276111
GO:0031175IEA-neuron projection development-
GO:0034394IDA-protein localization to cell surface18276111
GO:0034614IDA-cellular response to reactive oxygen species16849327
GO:0034644IDA-cellular response to UV16849327
GO:0035335IEA-peptidyl-tyrosine dephosphorylation-
GO:0045786IDA-negative regulation of cell cycle15899872
GO:0045892IDA-negative regulation of transcription, DNA-templated18276111
GO:0048041IMP-focal adhesion assembly15899872
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPRKCTNNB11078808663237 Affinity Capture-Western; Reconstituted Complex
PTPRKCTNNB11117608663237 Affinity Capture-Western; Reconstituted Complex
PTPRKJUP1099318663237 Affinity Capture-Western; Reconstituted Complex
PTPRKJUP1117608663237 Affinity Capture-Western; Reconstituted Complex
PTPRKPSMD1111168916169070 Two-hybrid
PTPRKPSMD1111176016169070 Two-hybrid
TK1PTPRK11293816169070 Two-hybrid
TK1PTPRK11176016169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103310
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9834'