AutismKB 2.0

Annotation Details for PTPRM


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PTPRM ( MGC166994,PTPRL1,R-PTP-MU,RPTPM,RPTPU,hR-PTPu )
Gene Full Name: protein tyrosine phosphatase, receptor type, M
Band: 18p11.23
Quick LinksEntrez ID:5797; OMIM: 176888; Uniprot ID:PTPRM_HUMAN; ENSEMBL ID: ENSG00000173482; HGNC ID: 9675
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm16380380
GO:0005886IDA-plasma membrane-
GO:0005887NAS-integral component of plasma membrane1655529
GO:0005911IDA-cell-cell junction15491993
GO:0005913IDA-cell-cell adherens junction17965016
GO:0030027IDA-lamellipodium15706045
GO:0048471IDA-perinuclear region of cytoplasm15491993
GO ID Evidence Qualifier GO_term References
GO:0004725IDA-protein tyrosine phosphatase activity8393854
GO:0005001IDA-transmembrane receptor protein tyrosine phosphatase activity10809770
GO:0005515IPI-protein binding9531566
GO:0042802IPI-identical protein binding10809770
GO:0045296IDA-cadherin binding9531566
GO ID Evidence Qualifier GO_term References
GO:0001937IMP-negative regulation of endothelial cell proliferation18566238
GO:0006470IDA-protein dephosphorylation8393854
GO:0007156IDA-homophilic cell adhesion via plasma membrane adhesion molecules8393854
GO:0007165IDA-signal transduction15080886
GO:0010596IMP-negative regulation of endothelial cell migration18566238
GO:0010842IMP-retina layer formation14623235
GO:0016525IMP-negative regulation of angiogenesis18566238
GO:0031175IDA-neuron projection development16380380
GO:0031175IMP-neuron projection development17276081
GO:0031290IDA-retinal ganglion cell axon guidance15080886
GO:0035335IEA-peptidyl-tyrosine dephosphorylation-
GO:0042493IDA-response to drug18566238
GO:0097755IEA-positive regulation of blood vessel diameter-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPRMCTNND110788110753936 Affinity Capture-Western; Biochemical Activity
PTPRMCTNND111176110753936 Affinity Capture-Western; Biochemical Activity
GNB2L1PTPRM11567111278757 11801604 Affinity Capture-Western; Two-hybrid
GNB2L1PTPRM11176111278757 11801604 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:102694
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-101108-4'