AutismKB 2.0

Annotation Details for ACTA1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ACTA1 ( ACTA,ASMA,CFTD,CFTD1,CFTDM,MPFD,NEM1,NEM2,NEM3 )
Gene Full Name: actin, alpha 1, skeletal muscle
Band: 1q42.13
Quick LinksEntrez ID:58; OMIM: 102610; Uniprot ID:ACTS_HUMAN; ENSEMBL ID: ENSG00000143632; HGNC ID: 129
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001725IDA-stress fiber15198992
GO:0005615IDA-extracellular space23580065
GO:0005829TAS-cytosol-
GO:0005865IDA-striated muscle thin filament15198992
GO:0005884IDA-actin filament12849983
GO:0015629IMP-actin cytoskeleton15198992
GO:0030017IDA-sarcomere1423520
GO:0030027ISS-lamellipodium-
GO:0030175ISS-filopodium-
GO:0044297ISS-cell body-
GO:0070062IDA-extracellular exosome19199708
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0005200TAS-structural constituent of cytoskeleton10508519
GO:0005515IPI-protein binding12849983
GO:0005524TAS-ATP binding10508519
GO:0017022TAS-myosin binding10508519
GO:0043531TAS-ADP binding10508519
GO ID Evidence Qualifier GO_term References
GO:0006936TAS-muscle contraction10508519
GO:0009612IEA-response to mechanical stimulus-
GO:0009991IEA-response to extracellular stimulus-
GO:0010226IEA-response to lithium ion-
GO:0010628ISS-positive regulation of gene expression-
GO:0016049IEA-cell growth-
GO:0030049TAS-muscle filament sliding-
GO:0030240IMP-skeletal muscle thin filament assembly11333380
GO:0043503IEA-skeletal muscle fiber adaptation-
GO:0048545IEA-response to steroid hormone-
GO:0048741ISS-skeletal muscle fiber development-
GO:0090131ISS-mesenchyme migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DMDACTA11080961544421 Reconstituted Complex
DMDACTA11065731544421 Reconstituted Complex
CNN1ACTA11065732161834 Reconstituted Complex
CNN1ACTA11076642161834 Reconstituted Complex
TMSB4YACTA11065738416954 Reconstituted Complex
TMSB4YACTA11145438416954 Reconstituted Complex
FSCN1ACTA11065738999969 Reconstituted Complex
FSCN1ACTA11125088999969 Reconstituted Complex
TMSB4XACTA11065739153421 11812134 Reconstituted Complex
TMSB4XACTA11129699153421 11812134 Reconstituted Complex
ETV6ACTA11065739695962 Co-localization
ETV6ACTA11084219695962 Co-localization
NRAPACTA110657310320340 Reconstituted Complex
NRAPACTA111095110320340 Reconstituted Complex
GSNACTA110918910583954 Co-crystal Structure
GSNACTA110657310583954 Co-crystal Structure
TSC1ACTA111309910806479 Co-localization
TSC1ACTA110657310806479 Co-localization
TAGLNACTA111273911053353 Co-fractionation
TAGLNACTA110657311053353 Co-fractionation
HDAC1ACTA110657311102443 Affinity Capture-MS
HDAC1ACTA110931511102443 Affinity Capture-MS
COTL1ACTA110657311297527 Reconstituted Complex
COTL1ACTA111697911297527 Reconstituted Complex
SPTAN1ACTA110657311441066 Affinity Capture-Western
SPTAN1ACTA111258711441066 Affinity Capture-Western
VIMACTA110657311441066 Affinity Capture-Western
VIMACTA111327211441066 Affinity Capture-Western
CCT4ACTA111582611580270 Co-crystal Structure
CCT4ACTA110657311580270 Co-crystal Structure
CCT5ACTA111660311580270 Co-crystal Structure
CCT5ACTA110657311580270 Co-crystal Structure
PCYT1BACTA110657311580270 Co-crystal Structure
PCYT1BACTA111485411580270 Co-crystal Structure
DHX9ACTA110657311687588 Affinity Capture-Western; Co-purification; Reconstituted Complex
DHX9ACTA110802511687588 Affinity Capture-Western; Co-purification; Reconstituted Complex
APC2ACTA110657311691822 Co-localization
APC2ACTA111558511691822 Co-localization
PRKCEACTA111156711897493 Affinity Capture-MS; Affinity Capture-Western
PRKCEACTA110657311897493 Affinity Capture-MS; Affinity Capture-Western
CFL1ACTA110657311950878 Affinity Capture-MS
CFL1ACTA110749911950878 Affinity Capture-MS
CSNK1A1ACTA110657312062430 Affinity Capture-MS
CSNK1A1ACTA110783612062430 Affinity Capture-MS
DVL1L1ACTA110657312384700 Affinity Capture-Western
DVL1L1ACTA111385112384700 Affinity Capture-Western
PPP1R9BACTA112420212417592 Reconstituted Complex
PPP1R9BACTA110657312417592 Reconstituted Complex
SCINACTA112455212438125 Reconstituted Complex
SCINACTA110657312438125 Reconstituted Complex
CDH2ACTA110657312438242 Affinity Capture-Western
CDH2ACTA110743512438242 Affinity Capture-Western
GCACTA110890812554937 Co-crystal Structure
GCACTA110657312554937 Co-crystal Structure
GRB2ACTA110657312577067 Affinity Capture-MS
GRB2ACTA110914212577067 Affinity Capture-MS
TESACTA111757212695497 Affinity Capture-Western
TESACTA110657312695497 Affinity Capture-Western
TNNI3KACTA110657312721663 Two-hybrid
TNNI3KACTA111927612721663 Two-hybrid
DNMBPACTA110657314506234 Affinity Capture-MS
DNMBPACTA111686914506234 Affinity Capture-MS
MIB2ACTA112676914507647 Reconstituted Complex; Two-hybrid
MIB2ACTA110657314507647 Reconstituted Complex; Two-hybrid
XPO6ACTA110657314592989 Affinity Capture-MS
XPO6ACTA111682114592989 Affinity Capture-MS
MARK4ACTA110657314594945 Affinity Capture-MS
MARK4ACTA112176014594945 Affinity Capture-MS
PFDN1ACTA110657314634002 Reconstituted Complex
PFDN1ACTA111122314634002 Reconstituted Complex
KLHL20ACTA111810014668487 Reconstituted Complex
KLHL20ACTA110657314668487 Reconstituted Complex
TRIP6ACTA110657314688263 Co-localization
TRIP6ACTA111305614688263 Co-localization
MLPHACTA110657315059972 Affinity Capture-Western
MLPHACTA112253115059972 Affinity Capture-Western
PHACTR1ACTA112874615107502 Affinity Capture-Western
PHACTR1ACTA110657315107502 Affinity Capture-Western
PPP1CAACTA110657315107502 Affinity Capture-Western
PPP1CAACTA111149315107502 Affinity Capture-Western
RPS6KB1ACTA111211215149849 Reconstituted Complex
RPS6KB1ACTA110657315149849 Reconstituted Complex
HDAC8ACTA110657315772115 Affinity Capture-Western
HDAC8ACTA112096815772115 Affinity Capture-Western
USP25ACTA110657316501887 Reconstituted Complex; Two-hybrid
USP25ACTA111889516501887 Reconstituted Complex; Two-hybrid
AKT1ACTA110657316568092 Affinity Capture-Western
AKT1ACTA110671016568092 Affinity Capture-Western
SMARCB1ACTA110657316568092 Affinity Capture-Western
SMARCB1ACTA111248216568092 Affinity Capture-Western
CTNNBL1ACTA112112321385873 Affinity Capture-MS
CTNNBL1ACTA110657321385873 Affinity Capture-MS
HDAC4ACTA110657321464227 Reconstituted Complex
HDAC4ACTA111510621464227 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:87902
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-55'