AutismKB 2.0

Annotation Details for PTPRS


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Basic Information Top
Gene Symbol:PTPRS ( PTPSIGMA )
Gene Full Name: protein tyrosine phosphatase, receptor type, S
Band: 19p13.3
Quick LinksEntrez ID:5802; OMIM: 601576; Uniprot ID:PTPRS_HUMAN; ENSEMBL ID: ENSG00000105426; HGNC ID: 9681
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886IDA-plasma membrane26231120
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane8524829
GO:0030054IEA-cell junction-
GO:0030285ISS-integral component of synaptic vesicle membrane-
GO:0030424ISS-axon-
GO:0043204IEA-perikaryon-
GO:0070062IDA-extracellular exosome23376485
GO:0099061ISS-integral component of postsynaptic density membrane-
GO ID Evidence Qualifier GO_term References
GO:0004721IDA-phosphoprotein phosphatase activity8524829
GO:0004725ISS-protein tyrosine phosphatase activity-
GO:0005515IPI-protein binding16273344
GO:0008201ISS-heparin binding-
GO:0035374ISS-chondroitin sulfate binding-
GO:0043395ISS-heparan sulfate proteoglycan binding-
GO ID Evidence Qualifier GO_term References
GO:0006470IDA-protein dephosphorylation8524829
GO:0007155IEA-cell adhesion-
GO:0010977ISS-negative regulation of neuron projection development-
GO:0021510IEA-spinal cord development-
GO:0021549IEA-cerebellum development-
GO:0021766IEA-hippocampus development-
GO:0021987IEA-cerebral cortex development-
GO:0022038IEA-corpus callosum development-
GO:0030517ISS-negative regulation of axon extension-
GO:0032687IMP-negative regulation of interferon-alpha production26231120
GO:0032688IMP-negative regulation of interferon-beta production26231120
GO:0034164IMP-negative regulation of toll-like receptor 9 signaling pathway26231120
GO:0035335ISS-peptidyl-tyrosine dephosphorylation-
GO:0048671ISS-negative regulation of collateral sprouting-
GO:0048681ISS-negative regulation of axon regeneration-
GO:0061000ISS-negative regulation of dendritic spine development-
GO:0090557IEA-establishment of endothelial intestinal barrier-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PTPRSCHD310753216169070 Two-hybrid
PTPRSCHD311176616169070 Two-hybrid
PTPRSEEF1G10825716169070 Two-hybrid
PTPRSEEF1G11176616169070 Two-hybrid
PTPRSEIF4A210829017353931 Affinity Capture-MS
PTPRSEIF4A211176617353931 Affinity Capture-MS
PTPRSPFN211123816169070 Two-hybrid
PTPRSPFN211176616169070 Two-hybrid
PTPRSPTN11173116169070 Two-hybrid
PTPRSPTN11176616169070 Two-hybrid
PTPRSPTPRD1117539566880 Affinity Capture-Western; Two-hybrid
PTPRSPTPRD1117669566880 Affinity Capture-Western; Two-hybrid
PPFIA1PTPRS1140728524829 9624153 Reconstituted Complex; Two-hybrid
PPFIA1PTPRS1117668524829 9624153 Reconstituted Complex; Two-hybrid
PPFIA2PTPRS1140719624153 Two-hybrid
PPFIA2PTPRS1117669624153 Two-hybrid
PPFIA3PTPRS1141119624153 Two-hybrid
PPFIA3PTPRS1117669624153 Two-hybrid
KAT5PTPRS11577916169070 Two-hybrid
KAT5PTPRS11176616169070 Two-hybrid
UTP14APTPRS11602616169070 Two-hybrid
UTP14APTPRS11176616169070 Two-hybrid
UBR1PTPRS12823816169070 Two-hybrid
UBR1PTPRS11176616169070 Two-hybrid
MOBKL3PTPRS11736916169070 Two-hybrid
MOBKL3PTPRS11176616169070 Two-hybrid
KIAA1377PTPRS12161716169070 Two-hybrid
KIAA1377PTPRS11176616169070 Two-hybrid
TUBB2APTPRS11313116169070 Two-hybrid
TUBB2APTPRS11176616169070 Two-hybrid
UNC119PTPRS11454816169070 Two-hybrid
UNC119PTPRS11176616169070 Two-hybrid
FEZ1PTPRS11499716169070 Two-hybrid
FEZ1PTPRS11176616169070 Two-hybrid
SETDB1PTPRS11520216169070 Two-hybrid
SETDB1PTPRS11176616169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97815
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-101103-2'