AutismKB 2.0

Annotation Details for MLL3


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Basic Information Top
Gene Symbol:MLL3 ( DKFZp686C08112,FLJ12625,FLJ38309,HALR,KIAA1506,KMT2C,MGC119851,MGC119852,MGC119853 )
Gene Full Name: myeloid/lymphoid or mixed-lineage leukemia 3
Band: 7q36.1
Quick LinksEntrez ID:58508; OMIM: 606833; Uniprot ID:MLL3_HUMAN; ENSEMBL ID: ENSG00000055609; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus17500065
GO:0005654TAS-nucleoplasm-
GO:0035097IDA-histone methyltransferase complex17500065
GO:0044666IDA-MLL3/4 complex17500065
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding12482968
GO:0016746IEA-transferase activity, transferring acyl groups-
GO:0018024TAS-histone-lysine N-methyltransferase activity-
GO:0042800IDA-histone methyltransferase activity (H3-K4 specific)17500065
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0051568IEA-histone H3-K4 methylation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MLL3AK112183517353931 Affinity Capture-MS
MLL3AK110670617353931 Affinity Capture-MS
MLL3ASCL212183512482968 Affinity Capture-Western
MLL3ASCL210692212482968 Affinity Capture-Western
MLL3MAPK1410781920936779 Two-hybrid
MLL3MAPK1412183520936779 Two-hybrid
MLL3H3F3A10927217403666 Affinity Capture-MS
MLL3H3F3A12183517403666 Affinity Capture-MS
MLL3JUN12183520936779 Two-hybrid
MLL3JUN10992820936779 Two-hybrid
MLL3RBBP512183512482968 17500065 Affinity Capture-Western; Co-purification
MLL3RBBP511186412482968 17500065 Affinity Capture-Western; Co-purification
MLL3SMARCB112183519221051 Reconstituted Complex; Two-hybrid
MLL3SMARCB111248219221051 Reconstituted Complex; Two-hybrid
MLL3KDM6A12183517761849 Affinity Capture-MS
MLL3KDM6A11324617761849 Affinity Capture-MS
MLL3ASH2L11452812482968 17500065 Affinity Capture-Western; Reconstituted Complex
MLL3ASH2L12183512482968 17500065 Affinity Capture-Western; Reconstituted Complex
MLL3PAXIP111662517500065 17925232 Affinity Capture-MS; Affinity Capture-Western; Co-purification
MLL3PAXIP112183517500065 17925232 Affinity Capture-MS; Affinity Capture-Western; Co-purification
MLL3NCOA612183512482968 17021013 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
MLL3NCOA611669112482968 17021013 19047629 Affinity Capture-MS; Affinity Capture-Western; Co-purification
HIST2H3CMLL312602512482968 Reconstituted Complex
HIST2H3CMLL312183512482968 Reconstituted Complex
C16orf53MLL312183517500065 Affinity Capture-Western
C16orf53MLL312267217500065 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2444959
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070705-340'