AutismKB 2.0

Annotation Details for RAB27A


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Basic Information Top
Gene Symbol:RAB27A ( GS2,HsT18676,MGC117246,RAB27,RAM )
Gene Full Name: RAB27A, member RAS oncogene family
Band: 15q21.3
Quick LinksEntrez ID:5873; OMIM: 603868; Uniprot ID:RB27A_HUMAN; ENSEMBL ID: ENSG00000069974; HGNC ID: 9766
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001750IEA-photoreceptor outer segment-
GO:0005576TAS-extracellular region-
GO:0005764IDA-lysosome15548590
GO:0005770IDA-late endosome17237785
GO:0005794IEA-Golgi apparatus-
GO:0005829TAS-cytosol-
GO:0016324IEA-apical plasma membrane-
GO:0030141IBA-secretory granule-
GO:0030425IDA-dendrite11266474
GO:0030667IEA-secretory granule membrane-
GO:0032585IDA-multivesicular body membrane19966785
GO:0033093IEA-Weibel-Palade body-
GO:0033162TAS-melanosome membrane-
GO:0035580TAS-specific granule lumen-
GO:0042470IDA-melanosome11266474
GO:0045202IEA-synapse-
GO:0070062IDA-extracellular exosome19056867
GO:0070382IDA-exocytic vesicle17237785
GO ID Evidence Qualifier GO_term References
GO:0003924ISS-GTPase activity-
GO:0005515IPI-protein binding12897212
GO:0005525IDA-GTP binding9066979
GO:0005525ISS-GTP binding-
GO:0019003IDA-GDP binding20937701
GO:0019904IEA-protein domain specific binding-
GO:0031489IEA-myosin V binding-
GO ID Evidence Qualifier GO_term References
GO:0006605IEA-protein targeting-
GO:0006887IDA-exocytosis18812475
GO:0007596IEA-blood coagulation-
GO:0010628IMP-positive regulation of gene expression23092844
GO:0019882IMP-antigen processing and presentation19717423
GO:0030318IEA-melanocyte differentiation-
GO:0032400IMP-melanosome localization15357836
GO:0032402IBA-melanosome transport-
GO:0036257IMP-multivesicular body organization23092844
GO:0043312TAS-neutrophil degranulation-
GO:0043316IEA-cytotoxic T cell degranulation-
GO:0043320IEA-natural killer cell degranulation-
GO:0045921IMP-positive regulation of exocytosis19966785
GO:0048489TAS-synaptic vesicle transport21563316
GO:0050766IMP-positive regulation of phagocytosis24404184
GO:0061024TAS-membrane organization-
GO:0071985IMP-multivesicular body sorting pathway19966785
GO:0097278IMP-complement-dependent cytotoxicity24404184
GO:1903307IGI-positive regulation of regulated secretory pathway22899725
GO:1903307IMP-positive regulation of regulated secretory pathway22899725
GO:1903428IMP-positive regulation of reactive oxygen species biosynthetic process24404184
GO:1903435IMP-positive regulation of constitutive secretory pathway22899725
GO:1990182IMP-exosomal secretion23092844
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RAB27AEEF1A110823716169070 Two-hybrid
RAB27AEEF1A111181116169070 Two-hybrid
RAB27AGDF910893016169070 Two-hybrid
RAB27AGDF911181116169070 Two-hybrid
RAB27AMYO5A11072812006666 12062444 Affinity Capture-Western; Reconstituted Complex
RAB27AMYO5A11181112006666 12062444 Affinity Capture-Western; Reconstituted Complex
EXPH5RAB27A11671511773082 Affinity Capture-Western
EXPH5RAB27A11181111773082 Affinity Capture-Western
SYTL3RAB27A12511911773082 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL3RAB27A11181111773082 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL2RAB27A12019411773082 11980908 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL2RAB27A11181111773082 11980908 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MLPHRAB27A12253111773082 11980908 12062444 15059972 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MLPHRAB27A11181111773082 11980908 12062444 15059972 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL1RAB27A11181111773082 11980908 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL1RAB27A12438911773082 11980908 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL4RAB27A12512011773082 11865063 12101244 12176990 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL4RAB27A11181111773082 11865063 12101244 12176990 12590134 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYTL5RAB27A12512112051743 12590134 Affinity Capture-Western; Reconstituted Complex
SYTL5RAB27A11181112051743 12590134 Affinity Capture-Western; Reconstituted Complex
RPH3ARAB27A11656012578829 Affinity Capture-Western
RPH3ARAB27A11181112578829 Affinity Capture-Western
RPH3ALRAB27A11488012578829 14593078 Affinity Capture-Western; Reconstituted Complex
RPH3ALRAB27A11181112578829 14593078 Affinity Capture-Western; Reconstituted Complex
MYRIPRAB27A11742412590134 Affinity Capture-Western
MYRIPRAB27A11181112590134 Affinity Capture-Western
UNC13DRAB27A12838314699162 Reconstituted Complex
UNC13DRAB27A11181114699162 Reconstituted Complex
COPS6RAB27A11617616169070 Two-hybrid
COPS6RAB27A11181116169070 Two-hybrid
C14orf1RAB27A11633216169070 Two-hybrid
C14orf1RAB27A11181116169070 Two-hybrid
C1orf103RAB27A12090516169070 Two-hybrid
C1orf103RAB27A11181116169070 Two-hybrid
KIAA1377RAB27A12161716169070 Two-hybrid
KIAA1377RAB27A11181116169070 Two-hybrid
ZBTB16RAB27A11349816169070 Two-hybrid
ZBTB16RAB27A11181116169070 Two-hybrid
C7orf64RAB27A12385516169070 Two-hybrid
C7orf64RAB27A11181116169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1861441
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050913-46'