Annotation Details for RAC2


Gene Symbol: | RAC2 ( EN-7,Gx,HSPC022 ) |
---|---|
Gene Full Name: | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
Band: | 22q13.1 |
Quick Links | Entrez ID:5880; OMIM: 602049; Uniprot ID:RAC2_HUMAN; ENSEMBL ID: ENSG00000128340; HGNC ID: 9802 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005635 | IEA | - | nuclear envelope | - |
GO:0005829 | IDA | - | cytosol | 19625648 |
GO:0005829 | TAS | - | cytosol | - |
GO:0005884 | IDA | colocalizes_with | actin filament | 19625648 |
GO:0005886 | TAS | - | plasma membrane | - |
GO:0005925 | IDA | - | focal adhesion | 21423176 |
GO:0030027 | IDA | - | lamellipodium | 19625648 |
GO:0030670 | TAS | - | phagocytic vesicle membrane | - |
GO:0070062 | IDA | - | extracellular exosome | 20458337 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0003924 | IEA | - | GTPase activity | - |
GO:0005525 | IMP | - | GTP binding | 19625648 |
GO:0019887 | IEA | - | protein kinase regulator activity | - |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0006935 | IEA | - | chemotaxis | - |
GO:0007015 | IMP | - | actin filament organization | 21167572 |
GO:0007165 | TAS | - | signal transduction | 2674130 |
GO:0007186 | IEA | - | G-protein coupled receptor signaling pathway | - |
GO:0007264 | IEA | - | small GTPase mediated signal transduction | - |
GO:0008284 | IEA | - | positive regulation of cell proliferation | - |
GO:0010310 | TAS | - | regulation of hydrogen peroxide metabolic process | 16636067 |
GO:0010592 | IMP | - | positive regulation of lamellipodium assembly | 19625648 |
GO:0010810 | IMP | - | regulation of cell-substrate adhesion | 21167572 |
GO:0030031 | IEA | - | cell projection assembly | - |
GO:0030168 | TAS | - | platelet activation | - |
GO:0042129 | IEA | - | regulation of T cell proliferation | - |
GO:0043304 | IEA | - | regulation of mast cell degranulation | - |
GO:0045453 | IEA | - | bone resorption | - |
GO:0045859 | IEA | - | regulation of protein kinase activity | - |
GO:0051056 | TAS | - | regulation of small GTPase mediated signal transduction | - |
GO:0060263 | IDA | - | regulation of respiratory burst | 16636067 |
GO:0060753 | IEA | - | regulation of mast cell chemotaxis | - |
GO:0071593 | IMP | - | lymphocyte aggregation | 21167572 |
GO:0090023 | IMP | - | positive regulation of neutrophil chemotaxis | 19625648 |
GO:1902622 | IMP | - | regulation of neutrophil migration | 21167572 |
GO:1903955 | IMP | - | positive regulation of protein targeting to mitochondrion | 24270810 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
RAC2 | ACTB | 106575 | 11027608 | Far Western |
RAC2 | ACTB | 111818 | 11027608 | Far Western |
RAC2 | ARHGDIA | 106889 | 9490022 11368848 | Co-purification; Two-hybrid |
RAC2 | ARHGDIA | 111818 | 9490022 11368848 | Co-purification; Two-hybrid |
RAC2 | ARHGDIB | 106890 | 10655614 | Co-crystal Structure |
RAC2 | ARHGDIB | 111818 | 10655614 | Co-crystal Structure |
RAC2 | DOCK2 | 111818 | 10559471 | Reconstituted Complex |
RAC2 | DOCK2 | 108129 | 10559471 | Reconstituted Complex |
RAC2 | NCF2 | 110768 | 9624165 9642115 | Reconstituted Complex; Two-hybrid |
RAC2 | NCF2 | 111818 | 9624165 9642115 | Reconstituted Complex; Two-hybrid |
RAC2 | NOS2 | 111818 | 11457725 | Affinity Capture-Western; Reconstituted Complex |
RAC2 | NOS2 | 110906 | 11457725 | Affinity Capture-Western; Reconstituted Complex |
RAC2 | PAK2 | 111098 | 12176041 | Reconstituted Complex |
RAC2 | PAK2 | 111818 | 12176041 | Reconstituted Complex |
ICMT | RAC2 | 111818 | 9614111 | Biochemical Activity |
ICMT | RAC2 | 117026 | 9614111 | Biochemical Activity |
CUL1 | RAC2 | 114032 | 11445862 | Two-hybrid |
CUL1 | RAC2 | 111818 | 11445862 | Two-hybrid |
DEF6 | RAC2 | 119099 | 15023524 | Reconstituted Complex |
DEF6 | RAC2 | 111818 | 15023524 | Reconstituted Complex |
No data |
No data |
- MGI ID: MGI:97846
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-040625-27