AutismKB 2.0

Annotation Details for RAC3


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Basic Information Top
Gene Symbol:RAC3 ( - )
Gene Full Name: ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Band: 17q25.3
Quick LinksEntrez ID:5881; OMIM: 602050; Uniprot ID:RAC3_HUMAN; ENSEMBL ID: ENSG00000169750; HGNC ID: 9803
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0005886TAS-plasma membrane-
GO:0012505IDA-endomembrane system11956649
GO:0030027IEA-lamellipodium-
GO:0030426IDA-growth cone16525025
GO:0031941IDA-filamentous actin16525025
GO:0043005IDA-neuron projection16525025
GO:0043025IDA-neuronal cell body16525025
GO:0048471IDA-perinuclear region of cytoplasm11756406
GO:0070062IDA-extracellular exosome23533145
GO:0071944IDA-cell periphery11756406
GO ID Evidence Qualifier GO_term References
GO:0003924IDA-GTPase activity11956649
GO:0005515IPI-protein binding11956649
GO:0005525IEA-GTP binding-
GO:0048306IPI-calcium-dependent protein binding11756406
GO ID Evidence Qualifier GO_term References
GO:0007264IEA-small GTPase mediated signal transduction-
GO:0014041IEA-regulation of neuron maturation-
GO:0021894IEA-cerebral cortex GABAergic interneuron development-
GO:0030031IDA-cell projection assembly11956649
GO:0030036IDA-actin cytoskeleton organization11956649
GO:0031175IEA-neuron projection development-
GO:0033630IDA-positive regulation of cell adhesion mediated by integrin11756406
GO:0035556TAS-intracellular signal transduction9252344
GO:0048873IEA-homeostasis of number of cells within a tissue-
GO:0050885IEA-neuromuscular process controlling balance-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0051932IEA-synaptic transmission, GABAergic-
GO:1900026IDA-positive regulation of substrate adhesion-dependent cell spreading11756406
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HNF1ARAC311278910777539 Affinity Capture-Western; Reconstituted Complex
CIB1RAC311577411756406 Affinity Capture-Western; Two-hybrid
CIB1RAC311181911756406 Affinity Capture-Western; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2180784
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-256'