AutismKB 2.0

Annotation Details for RAD51


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Basic Information Top
Gene Symbol:RAD51 ( BRCC5,HRAD51,HsRad51,HsT16930,RAD51A,RECA )
Gene Full Name: RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
Band: 15q15.1
Quick LinksEntrez ID:5888; OMIM: 179617; Uniprot ID:RAD51_HUMAN; ENSEMBL ID: ENSG00000051180; HGNC ID: 9817
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000228IDA-nuclear chromosome23754376
GO:0000784IDA-nuclear chromosome, telomeric region21076401
GO:0000785IDA-chromatin25585578
GO:0000790IDA-nuclear chromatin26323318
GO:0000793ISS-condensed chromosome-
GO:0000794ISS-condensed nuclear chromosome-
GO:0000800IDA-lateral element9774970
GO:0005634IDA-nucleus12442171
GO:0005634ISS-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005730IDA-nucleolus-
GO:0005737IDA-cytoplasm16215984
GO:0005739IDA-mitochondrion20413593
GO:0005759IEA-mitochondrial matrix-
GO:0005815IEA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0016605IDA-PML body11309417
GO:0035861IDA-site of double-strand break24550317
GO:0048471IDA-perinuclear region of cytoplasm16215984
GO ID Evidence Qualifier GO_term References
GO:0000150IBA-recombinase activity-
GO:0000400IBA-four-way junction DNA binding-
GO:0003682IEA-chromatin binding-
GO:0003690IDA-double-stranded DNA binding7988572
GO:0003690IMP-double-stranded DNA binding26681308
GO:0003697IDA-single-stranded DNA binding7988572
GO:0003697IMP-single-stranded DNA binding26681308
GO:0004520IBAcontributes_toendodeoxyribonuclease activity-
GO:0005515IPI-protein binding8675009
GO:0005524IDA-ATP binding16428451
GO:0008022IPI-protein C-terminus binding17515903
GO:0042802IPI-identical protein binding9396801
GO:0043142IDA-single-stranded DNA-dependent ATPase activity7988572
GO:0043142IMP-single-stranded DNA-dependent ATPase activity26681308
GO:0070182IPI-DNA polymerase binding19995904
GO ID Evidence Qualifier GO_term References
GO:0000722ISS-telomere maintenance via recombination21076401
GO:0000724IDA-double-strand break repair via homologous recombination16428451
GO:0000724IMP-double-strand break repair via homologous recombination22778135
GO:0000724TAS-double-strand break repair via homologous recombination12427746
GO:0000730IMP-DNA recombinase assembly26681308
GO:0000731TAS-DNA synthesis involved in DNA repair-
GO:0000732TAS-strand displacement-
GO:0001932IEA-regulation of protein phosphorylation-
GO:0006268IDA-DNA unwinding involved in DNA replication7988572
GO:0006281TAS-DNA repair8358431
GO:0006310TAS-DNA recombination7988572
GO:0006312TAS-mitotic recombination8358431
GO:0006974IDA-cellular response to DNA damage stimulus23509288
GO:0006974IMP-cellular response to DNA damage stimulus26681308
GO:0007131TAS-reciprocal meiotic recombination8358431
GO:0009636IEA-response to toxic substance-
GO:0010165IEA-response to X-ray-
GO:0010569IDA-regulation of double-strand break repair via homologous recombination23754376
GO:0010833ISS-telomere maintenance via telomere lengthening21076401
GO:0031297IDA-replication fork processing25585578
GO:0031297IMP-replication fork processing22778135
GO:0036297IMP-interstrand cross-link repair26253028
GO:0042148IBA-strand invasion-
GO:0042493IEA-response to drug-
GO:0051106IDA-positive regulation of DNA ligation8929543
GO:0051260IPI-protein homooligomerization12442171
GO:0051321ISS-meiotic cell cycle-
GO:0070192IBA-chromosome organization involved in meiotic cell cycle-
GO:0071479IDA-cellular response to ionizing radiation23509288
GO:0071480IEA-cellular response to gamma radiation-
GO:0072711IEA-cellular response to hydroxyurea-
GO:0072719IEA-cellular response to cisplatin-
GO:0072757IDA-cellular response to camptothecin23509288
GO:1904631IEA-response to glucoside-
GO:1990414IEA-replication-born double-strand break repair via sister chromatid exchange-
GO:1990426IEA-mitotic recombination-dependent replication fork processing-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RAD51ABL110654310212258 Affinity Capture-Western; Reconstituted Complex
RAD51ABL111182510212258 Affinity Capture-Western; Reconstituted Complex
RAD51ATM11182510212258 Affinity Capture-Western
RAD51ATM10696210212258 Affinity Capture-Western
RAD51ATRX11182510851248 12205100 15466868 Reconstituted Complex; Two-hybrid
RAD51ATRX10702810851248 12205100 15466868 Reconstituted Complex; Two-hybrid
RAD51BARD110705614636569 Affinity Capture-MS; Affinity Capture-Western
RAD51BARD111182514636569 Affinity Capture-MS; Affinity Capture-Western
RAD51BLM10711011278509 Affinity Capture-Western; Far Western; Two-hybrid
RAD51BLM11182511278509 Affinity Capture-Western; Far Western; Two-hybrid
RAD51BRCA11071409008167 9774970 11498787 14636569 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
RAD51BRCA11118259008167 9774970 11498787 14636569 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
RAD51BRCA21071429126738 9405383 9523196 9560268 9774970 9811893 11313963 11477095 12442171 12815053 14580352 14636569 15065660 15671039 16914443 Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid
RAD51BRCA21118259126738 9405383 9523196 9560268 9774970 9811893 11313963 11477095 12442171 12815053 14580352 14636569 15065660 15671039 16914443 Affinity Capture-MS; Affinity Capture-Western; Co-localization; Co-purification; Reconstituted Complex; Two-hybrid
RAD51CHD310753216169070 Two-hybrid
RAD51CHD311182516169070 Two-hybrid
RAD51LGTN11182517353931 Affinity Capture-MS
RAD51LGTN10825917353931 Affinity Capture-MS
RAD51H2AFX11182510959836 Co-localization
RAD51H2AFX10926810959836 Co-localization
RAD51MSH411182511950880 Co-localization
RAD51MSH411057511950880 Co-localization
RAD51RAD511118258610150 10851248 12442171 14580352 Affinity Capture-Western; Co-crystal Structure; Co-localization; Two-hybrid
UBE2IRAD511131778610150 8921390 Two-hybrid
UBE2IRAD511118258610150 8921390 Two-hybrid
TP53RAD511118258617246 9380510 14636569 16983346 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
TP53RAD511130108617246 9380510 14636569 16983346 Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
SUMO1RAD511131888812453 Two-hybrid
SUMO1RAD511118258812453 Two-hybrid
RAD51AP1RAD511118259396801 Reconstituted Complex; Two-hybrid
RAD51AP1RAD511158799396801 Reconstituted Complex; Two-hybrid
RAD52RAD5111183010212258 Affinity Capture-Western
RAD52RAD5111182510212258 Affinity Capture-Western
DMC1RAD5111631610562567 Reconstituted Complex; Two-hybrid
DMC1RAD5111182510562567 Reconstituted Complex; Two-hybrid
RAD54BRAD5111732110851248 Affinity Capture-Western; Reconstituted Complex
RAD54BRAD5111182510851248 Affinity Capture-Western; Reconstituted Complex
DNAJA3RAD5111454711005857 Co-localization
DNAJA3RAD5111182511005857 Co-localization
RPA1RAD5111182512077133 Reconstituted Complex
RPA1RAD5111203712077133 Reconstituted Complex
BRCC3RAD5112259914636569 Affinity Capture-MS; Affinity Capture-Western; Co-purification
BRCC3RAD5111182514636569 Affinity Capture-MS; Affinity Capture-Western; Co-purification
BRERAD5111182514636569 Affinity Capture-MS; Affinity Capture-Western; Co-purification
BRERAD5111494614636569 Affinity Capture-MS; Affinity Capture-Western; Co-purification
RAD51CRAD5111182515065660 16395335 Affinity Capture-Western; Co-localization
RAD51CRAD5111182615065660 16395335 Affinity Capture-Western; Co-localization
RAD51L1RAD5111182515065660 Co-localization
RAD51L1RAD5111182715065660 Co-localization
RAD51L3RAD5111182915065660 Co-localization
RAD51L3RAD5111182515065660 Co-localization
XRCC2RAD5111335015065660 Co-localization
XRCC2RAD5111182515065660 Co-localization
XRCC3RAD5111335115065660 Co-localization
XRCC3RAD5111182515065660 Co-localization
VIMRAD5111182516169070 Two-hybrid
VIMRAD5111327216169070 Two-hybrid
MDC1RAD5111501416186822 Affinity Capture-Western; Reconstituted Complex
MDC1RAD5111182516186822 Affinity Capture-Western; Reconstituted Complex
TIMM13RAD5111772217353931 Affinity Capture-MS
TIMM13RAD5111182517353931 Affinity Capture-MS
CAB39RAD5111969617353931 Affinity Capture-MS
CAB39RAD5111182517353931 Affinity Capture-MS
SP1RAD5111182518769160 Affinity Capture-Western
SP1RAD5111255018769160 Affinity Capture-Western
RAD18RAD5112121219396164 Affinity Capture-Western; Reconstituted Complex
RAD18RAD5111182519396164 Affinity Capture-Western; Reconstituted Complex
MCPH1RAD5112277619549900 20107607 Affinity Capture-Western; Co-localization
MCPH1RAD5111182519549900 20107607 Affinity Capture-Western; Co-localization
PALB2RAD5112284320871616 Reconstituted Complex
PALB2RAD5111182520871616 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:97890
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-2286'