AutismKB 2.0

Annotation Details for RALGDS


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Basic Information Top
Gene Symbol:RALGDS ( FLJ20922,RGDS,RGF,RalGEF )
Gene Full Name: ral guanine nucleotide dissociation stimulator
Band: 9q34.13-q34.2
Quick LinksEntrez ID:5900; OMIM: 601619; Uniprot ID:GNDS_HUMAN; ENSEMBL ID: ENSG00000160271; HGNC ID: 9842
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus22797597
GO:0005829IDA-cytosol22797597
GO:0005829TAS-cytosol-
GO:0005903IDA-brush border22797597
GO ID Evidence Qualifier GO_term References
GO:0005085IEA-guanyl-nucleotide exchange factor activity-
GO:0005515IPI-protein binding20936779
GO:0030695IDA-GTPase regulator activity7972015
GO:0030695NAS-GTPase regulator activity9365783
GO ID Evidence Qualifier GO_term References
GO:0007265TAS-Ras protein signal transduction-
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RALGDSARRB110690112105416 Affinity Capture-Western
RALGDSARRB111183612105416 Affinity Capture-Western
RALGDSARRB210690212105416 Affinity Capture-Western; Two-hybrid
RALGDSARRB211183612105416 Affinity Capture-Western; Two-hybrid
RALGDSHRAS1095017809086 7972015 9038168 9150145 9154803 10783161 10922060 15031288 20936779 Reconstituted Complex; Two-hybrid
RALGDSHRAS1118367809086 7972015 9038168 9150145 9154803 10783161 10922060 15031288 20936779 Reconstituted Complex; Two-hybrid
RALGDSKRAS1100437809086 10783161 Reconstituted Complex; Two-hybrid
RALGDSKRAS1118367809086 10783161 Reconstituted Complex; Two-hybrid
RALGDSLRPAP111022110783161 Two-hybrid
RALGDSLRPAP111183610783161 Two-hybrid
RALGDSPDK111118911889038 Affinity Capture-Western
RALGDSPDK111183611889038 Affinity Capture-Western
RRASRALGDS1121517809086 Reconstituted Complex; Two-hybrid
RRASRALGDS1118367809086 Reconstituted Complex; Two-hybrid
RAPGEF2RALGDS1150457809086 Reconstituted Complex; Two-hybrid
RAPGEF2RALGDS1118367809086 Reconstituted Complex; Two-hybrid
MRASRALGDS1164869400994 10498616 Reconstituted Complex; Two-hybrid
MRASRALGDS1118369400994 10498616 Reconstituted Complex; Two-hybrid
RAP2ARALGDS11184610085114 Affinity Capture-Western; Reconstituted Complex
RAP2ARALGDS11183610085114 Affinity Capture-Western; Reconstituted Complex
RAP2BRALGDS11184710085114 Reconstituted Complex
RAP2BRALGDS11183610085114 Reconstituted Complex
RAP1ARALGDS11184110085114 10922060 Reconstituted Complex; Two-hybrid
RAP1ARALGDS11183610085114 10922060 Reconstituted Complex; Two-hybrid
RIT1RALGDS11194810545207 Two-hybrid
RIT1RALGDS11183610545207 Two-hybrid
RIN1RALGDS11497210545207 Two-hybrid
RIN1RALGDS11183610545207 Two-hybrid
RRAS2RALGDS11648011788587 Two-hybrid
RRAS2RALGDS11183611788587 Two-hybrid
CNKSR1RALGDS11555014749388 Affinity Capture-Western
CNKSR1RALGDS11183614749388 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
RALGDSHRAS1853049516482 Ras interacts with the carboxy terminus of RalGDS. This interaction was modeled on a demonstrated interaction between human Ras and rat RalGDS.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107485
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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