AutismKB 2.0

Annotation Details for RANGAP1


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Basic Information Top
Gene Symbol:RANGAP1 ( Fug1,KIAA1835,MGC20266,SD )
Gene Full Name: Ran GTPase activating protein 1
Band: 22q13.2
Quick LinksEntrez ID:5905; OMIM: 602362; Uniprot ID:RAGP1_HUMAN; ENSEMBL ID: ENSG00000100401; HGNC ID: 9854
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000776IDAcolocalizes_withkinetochore17363900
GO:0000777IEA-condensed chromosome kinetochore-
GO:0000922IEA-spindle pole-
GO:0005635IDA-nuclear envelope25468996
GO:0005635TAS-nuclear envelope-
GO:0005643TAS-nuclear pore8978815
GO:0005737TAS-cytoplasm8978815
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0016235IDA-aggresome-
GO:0030425IEA-dendrite-
GO:0031965IDA-nuclear membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0044614IEA-nuclear pore cytoplasmic filaments-
GO:0048471IDA-perinuclear region of cytoplasm26308891
GO:0072686IEA-mitotic spindle-
GO:1904115IEA-axon cytoplasm-
GO:1990723IEA-cytoplasmic periphery of the nuclear pore complex-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding26308891
GO:0005096IEA-GTPase activator activity-
GO:0005515IPI-protein binding17000644
GO:0008536IEA-Ran GTPase binding-
GO:0031625IEA-ubiquitin protein ligase binding-
GO:0045296IDA-cadherin binding25468996
GO ID Evidence Qualifier GO_term References
GO:0007062TAS-sister chromatid cohesion-
GO:0007165IEA-signal transduction-
GO:0016925TAS-protein sumoylation-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0046826IDA-negative regulation of protein export from nucleus16449645
GO:0048678IEA-response to axon injury-
GO:1904117IEA-cellular response to vasopressin-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RANGAP1PMS111184017148452 Affinity Capture-Western
RANGAP1PMS111139117148452 Affinity Capture-Western
RANGAP1RAN1118407744835 8146159 10394366 Reconstituted Complex
RANGAP1RAN1118377744835 8146159 10394366 Reconstituted Complex
RANGAP1RANGAP11118408146159 Co-purification
UBE2IRANGAP111317712924945 17353931 18691969 Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
UBE2IRANGAP111184012924945 17353931 18691969 Affinity Capture-MS; Biochemical Activity; Reconstituted Complex
SUMO1RANGAP111318812924945 Reconstituted Complex
SUMO1RANGAP111184012924945 Reconstituted Complex
SUMO3RANGAP111249616620772 Affinity Capture-MS
SUMO3RANGAP111184016620772 Affinity Capture-MS
SUMO2RANGAP111184016620772 Affinity Capture-MS
SUMO2RANGAP111249716620772 Affinity Capture-MS
MEPCERANGAP112112217643375 Affinity Capture-MS
MEPCERANGAP111184017643375 Affinity Capture-MS
TOPORSRANGAP111184017803295 Affinity Capture-MS
TOPORSRANGAP111550517803295 Affinity Capture-MS
C19orf62RANGAP111885519615732 Affinity Capture-MS
C19orf62RANGAP111184019615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:103071
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1921'