AutismKB 2.0

Annotation Details for RAP1GDS1


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Basic Information Top
Gene Symbol:RAP1GDS1 ( GDS1,MGC118859,MGC118861,SmgGDS )
Gene Full Name: RAP1, GTP-GDP dissociation stimulator 1
Band: 4q23
Quick LinksEntrez ID:5910; OMIM: 179502; Uniprot ID:GDS1_HUMAN; ENSEMBL ID: ENSG00000138698; HGNC ID: 9859
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion24349085
GO:0005783IDA-endoplasmic reticulum24349085
GO:0005829IDA-cytosol24349085
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005096NAS-GTPase activator activity1549351
GO:0005515IPI-protein binding25416956
GO ID Evidence Qualifier GO_term References
GO:0014829IEA-vascular smooth muscle contraction-
GO:0031034IEA-myosin filament assembly-
GO:0032471IMP-negative regulation of endoplasmic reticulum calcium ion concentration24349085
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051561IMP-positive regulation of mitochondrial calcium ion concentration24349085
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RAP1GDS1RHOA11184511948427 Reconstituted Complex; Two-hybrid
RAP1GDS1RHOA10688011948427 Reconstituted Complex; Two-hybrid
RAP1GDS1CDC4211184520936779 Two-hybrid
RAP1GDS1CDC4210743320936779 Two-hybrid
RAP1GDS1EGFR11184520029029 PCA
RAP1GDS1EGFR10827620029029 PCA
RAP1GDS1HRAS10950111948427 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RAP1GDS1HRAS11184511948427 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RAP1GDS1KRAS11184511948427 Two-hybrid
RAP1GDS1KRAS11004311948427 Two-hybrid
RAP1GDS1NRAS11095211948427 Two-hybrid
RAP1GDS1NRAS11184511948427 Two-hybrid
RAP1GDS1RAC111184511948427 20936779 Two-hybrid
RAP1GDS1RAC111181711948427 20936779 Two-hybrid
RAP1GDS1RAP1A11184111948427 Two-hybrid
RAP1GDS1RAP1A11184511948427 Two-hybrid
KIFAP3RAP1GDS11165828900189 Reconstituted Complex; Two-hybrid
KIFAP3RAP1GDS11118458900189 Reconstituted Complex; Two-hybrid
ZNF451RAP1GDS111184516189514 Two-hybrid
ZNF451RAP1GDS111750216189514 Two-hybrid
MBIPRAP1GDS111961216189514 Two-hybrid
MBIPRAP1GDS111184516189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2385189
  • Data Attributes: MGI curated and HomoloGene calculated
No data