AutismKB 2.0

Annotation Details for ACE2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ACE2 ( ACEH,DKFZp434A014 )
Gene Full Name: angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Band: Xp22.2
Quick LinksEntrez ID:59272; OMIM: 300335; Uniprot ID:ACE2_HUMAN; ENSEMBL ID: ENSG00000130234; HGNC ID: 13557
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IDA-extracellular region10969042
GO:0005615IDA-extracellular space18258853
GO:0005737IEA-cytoplasm-
GO:0005886IDA-plasma membrane21068237
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface18343844
GO:0016021IEA-integral component of membrane-
GO:0045121TAS-membrane raft18279660
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0001618IDA-virus receptor activity18343844
GO:0001618IMP-virus receptor activity24227843
GO:0001948IPI-glycoprotein binding18343844
GO:0004175IDA-endopeptidase activity15283675
GO:0004180IDA-carboxypeptidase activity10924499
GO:0004181EXP-metallocarboxypeptidase activity10924499
GO:0005515IPI-protein binding21068237
GO:0008237IDANOTmetallopeptidase activity10924499
GO:0008241IDANOTpeptidyl-dipeptidase activity10924499
GO:0008270TAS-zinc ion binding10924499
GO ID Evidence Qualifier GO_term References
GO:0001817IC-regulation of cytokine production15380922
GO:0002003TAS-angiotensin maturation-
GO:0002005IC-angiotensin catabolic process in blood10924499
GO:0003051IMP-angiotensin-mediated drinking behavior18258853
GO:0003081IC-regulation of systemic arterial blood pressure by renin-angiotensin10924499
GO:0003081IMP-regulation of systemic arterial blood pressure by renin-angiotensin18258853
GO:0015827IEA-tryptophan transport-
GO:0019229IC-regulation of vasoconstriction15380922
GO:0032800IMP-receptor biosynthetic process18258853
GO:0042127TAS-regulation of cell proliferation17703127
GO:0046718TAS-viral entry into host cell15165741
GO:0046813IDA-receptor-mediated virion attachment to host cell18343844
GO:0050727IC-regulation of inflammatory response15380922
GO:0060452IEA-positive regulation of cardiac muscle contraction-
GO:0097746IC-regulation of blood vessel diameter15380922
GO:1903598IMP-positive regulation of gap junction assembly12967627
GO:1903779IMP-regulation of cardiac conduction12967627
GO:2000379IC-positive regulation of reactive oxygen species metabolic process15380922
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1917258
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041114-6'