AutismKB 2.0

Annotation Details for RBL2


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Basic Information Top
Gene Symbol:RBL2 ( FLJ26459,P130,Rb2 )
Gene Full Name: retinoblastoma-like 2 (p130)
Band: 16q12.2
Quick LinksEntrez ID:5934; OMIM: 180203; Uniprot ID:RBL2_HUMAN; ENSEMBL ID: ENSG00000103479; HGNC ID: 9894
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus-
GO:0005654TAS-nucleoplasm-
GO:0005667IEA-transcription factor complex-
GO:0005730IDA-nucleolus-
GO:0005829IDA-cytosol-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0005515IPI-protein binding1331501
GO:1990841IDA-promoter-specific chromatin binding25100735
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0006357IEA-regulation of transcription from RNA polymerase II promoter-
GO:0006977TAS-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-
GO:0010629IMP-negative regulation of gene expression25100735
GO:0016569IEA-covalent chromatin modification-
GO:0043550IDA-regulation of lipid kinase activity16286473
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RBL2BRCA110714011521194 Co-localization; Reconstituted Complex
RBL2BRCA111186911521194 Co-localization; Reconstituted Complex
RBL2CCNA21118698253383 Affinity Capture-Western
RBL2CCNA21073318253383 Affinity Capture-Western
RBL2CCNE11118698253383 9891079 Affinity Capture-Western
RBL2CCNE11073388253383 9891079 Affinity Capture-Western
RBL2CDK21118699188854 9891079 Biochemical Activity; Reconstituted Complex
RBL2CDK21074529188854 9891079 Biochemical Activity; Reconstituted Complex
RBL2E2F41082069858615 Affinity Capture-Western
RBL2E2F41118699858615 Affinity Capture-Western
RBL2E2F51082077760804 Co-purification
RBL2E2F51118697760804 Co-purification
RBL2EZH210844615077161 Affinity Capture-Western; Reconstituted Complex
RBL2EZH211186915077161 Affinity Capture-Western; Reconstituted Complex
RBL2BRF111186910330166 Affinity Capture-Western; Reconstituted Complex
RBL2BRF110922710330166 Affinity Capture-Western; Reconstituted Complex
RBL2HDAC11118699724731 9858615 10969803 Affinity Capture-Western
RBL2HDAC11093159724731 9858615 10969803 Affinity Capture-Western
RBL2ID211186916776654 Affinity Capture-Western
RBL2ID210962416776654 Affinity Capture-Western
RBL2MCM71118699566894 Reconstituted Complex
RBL2MCM71103449566894 Reconstituted Complex
RBL2SERPINB211186916397580 Affinity Capture-Western
RBL2SERPINB211109216397580 Affinity Capture-Western
RBL2PCBD111186920211142 Two-hybrid
RBL2PCBD111112520211142 Two-hybrid
RBL2PHB11126410376528 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RBL2PHB11186910376528 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RBL2PPP2CA11186912915404 Reconstituted Complex
RBL2PPP2CA11150712915404 Reconstituted Complex
RBL2RAF11118319819434 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RBL2RAF11118699819434 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RBL2RB111186910490602 Affinity Capture-Western
RBL2RB111186010490602 Affinity Capture-Western
RBL2RBBP81118699721205 10449734 Affinity Capture-Western; Two-hybrid
RBL2RBBP81118679721205 10449734 Affinity Capture-Western; Two-hybrid
HBP1RBL21179279178770 Two-hybrid
HBP1RBL21118699178770 Two-hybrid
TAF1RBL21127359242374 Affinity Capture-Western
TAF1RBL21118699242374 Affinity Capture-Western
RBBP9RBL21159649697699 Affinity Capture-Western
RBBP9RBL21118699697699 Affinity Capture-Western
CCNA1RBL211441710022926 Reconstituted Complex
CCNA1RBL211186910022926 Reconstituted Complex
USP4RBL211186911571651 Reconstituted Complex
USP4RBL211322111571651 Reconstituted Complex
AATFRBL211186912450794 Affinity Capture-Western
AATFRBL211774312450794 Affinity Capture-Western
SNW1RBL211186912466551 Reconstituted Complex
SNW1RBL211659712466551 Reconstituted Complex
SUV39H1RBL211186912588981 Affinity Capture-Western
SUV39H1RBL211270612588981 Affinity Capture-Western
SKP1RBL211186912717421 Affinity Capture-Western
SKP1RBL211239112717421 Affinity Capture-Western
SKP2RBL211186912717421 Affinity Capture-Western
SKP2RBL211239312717421 Affinity Capture-Western
UBCRBL211186912717421 12915404 Affinity Capture-Western
UBCRBL211316412717421 12915404 Affinity Capture-Western
CUL1RBL211403212717421 Affinity Capture-Western
CUL1RBL211186912717421 Affinity Capture-Western
XBP1RBL211333120211142 Two-hybrid
XBP1RBL211186920211142 Two-hybrid
Gene Symbol Interactant Interaction ID References Description
RBL2MCM71834169566894 MCM7 interacts with p130.
RBL2MDM219732715577944 p130 interacts with Mdm2.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:105085
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-061109-2'